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The Red Queen in the Repository: metadata quality in an ever-changing environ...
This fileset contains a preprint version of the conference paper (.pdf), presentation slides (as .pptx) and the dataset(s) and validation schema(s) for the IDCC 2019 (Melbourne)... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated... -
Etomidate decreases adrenal gland apoptosis and necrosis associated with hemo...
Purpose: Evaluate if etomidate modulates adrenal apoptosis and if this influences the development of critical illness-related corticosteroid insufficiency (CIRCI) in hemorrhagic... -
dedup_wf_001--cedafc998d1fc5debcd248d1a74f7628
Figure S1. Schematic of drug-inducible sgRNA expression lentiviral vectors. Figure S2. Nucleotide sequence presentation of the DOX- and IPTG-inducible U6 promoter variants used... -
Additional file 2 of Impact of malnutrition on systemic immune and metabolic ...
Additional file 2: Table S1. -
dedup_wf_001--7d3a242d53edf571a7027e17a722d996
Additional file 2. Map of the porcine mitochondrial DNA. Localisation of the 721Â bp long control region (CR) fragment in the reference mitochondrial genome. -
Function of <i>PoLAE2</i>, a <i>laeA</i> homolog, in appressorium formation a...
A novel homolog of laeA, a global regulatory gene in filamentous fungi, was identified from Pyricularia oryzae. A deletion mutant of the homolog (PoLAE2) exhibited lowered... -
Emergency Medical Services Care and Sepsis Trajectories
Objective: Many sepsis patients receive initial care from prehospital Emergency Medical Services (EMS). While earlier sepsis care improves outcomes, the characteristics, care... -
dedup_wf_001--678de25d4a66913eeaf6f1bd36b33ffe
Additional file 1. Representative standard curve and amplification plot from each let-7 family member RT-qPCR. Standard curve and amplification plot from (A) let-7a, (B) let-7b,... -
Additional file 6: Figure S5. of Development of an integrated approach for co...
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) (A), interleukin (IL)-1α (B), IL-1β (C), IL-5 (D), IL-10 (E), Keratinocyte-derived Chemokine (KC) (F), Macrophage... -
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming gro...
Abstract Background Pirfenidone, an antifibrotic agent used for the treatment of idiopathic pulmonary fibrosis (IPF), functions by inhibiting myofibroblast differentiation,... -
Study dataset.
Compliance with NPG checklist items: data dictionary available in project space. In version 2, 7 errors from the previous version at database lock (publication date for PMID... -
TRPV1 mediates astrocyte activation and interleukin-1β release induced by hyp...
Abstract Background Hypoxic-ischemic encephalopathy (HIE) is a serious birth complication with high incidence in both advanced and developing countries. Children surviving from... -
Additional file 2 of Metabolic characterization of aggressive breast cancer c...
Additional file 2: Supplemental Figure 2. Mitochondrial membrane potential of SUM149 invading cells. -
Additional file 1 of Impact of malnutrition on systemic immune and metabolic ...
Additional file 1: Figure S1. Flowchart for the study participant recruitment. A flowchart illustrating participant recruitment to the study. -
The human fetal adrenal produces cortisol but no detectable aldosterone throu...
Abstract Background Human fetal adrenal glands are highly active and, with the placenta, regulate circulating progesterone, estrogen and corticosteroids in the fetus. At birth... -
Single nucleotide polymorphisms in apoptosis pathway are associated with resp...
Abstract Background The mechanism of action of imatinib is known to involve the Fas-mediated apoptosis pathway. Consequently inter-individual variations in this apoptosis... -
Additional file 3: Figure S3. of Thrombin-induced, TNFR-dependent miR-181c do...
Schematic overview of thrombin’s effects upon miR-181c and MLL1 in human microglia. Thrombin (via PAR4) induces TNF-α secretion from human microglia [21]. Thrombin-induced TNF-α... -
Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress ...
Abstract Background Ischemia–reperfusion (I/R)-induced acute kidney injury (AKI) not only prolongs the length of hospital stay, but also seriously affects the patient’s survival... -
Regulatory role of heme oxygenase-1 in silica-induced lung injury
Abstract Background Silicosis, a progressive inflammatory lung disease attributed mainly to occupational exposure to silica dust, shows loss of lung function even after...
