Additional file 6: Figure S5. of Development of an integrated approach for comparison of in vitro and in vivo responses to particulate matter

Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) (A), interleukin (IL)-1α (B), IL-1β (C), IL-5 (D), IL-10 (E), Keratinocyte-derived Chemokine (KC) (F), Macrophage Inflammatory Protein (MIP)-1α (G), Regulated upon Activation Normal T cell Expressed and Secreted (RANTES) (H) and Tumor Necrosis Factor (TNF)-α (I) levels in bronchioalveolar lavage fluid of BALB/c mice exposed to particles by intratracheal instillation, at 24 h post-exposure. Values represent mean fold-effect (FE) ± standard error of the mean (n = 5). Two way ANOVA; GM-CSF, Dose main effect, p < 0.001, Dose 250 vs. 0 (†), Dose 250 vs. 50 (‡), Tukey test, p < 0.05; IL-1α, PM main effect, p < 0.001, CRI, EHC-2000 or SRM-1649 vs. DWR1 or TiO2 (†), Tukey test, p < 0.05, Dose main effect, p < 0.001, Dose 0 vs. 50, 100 or 250 (‡), Dose 50 vs. 100 (not shown), Dose 250 vs. 50 or 100 (not shown), Tukey test, p < 0.05; IL-β, PM × Dose interaction, p = 0.015, asterisks (*) represent effects significantly different from Dose 0 control, Tukey test, p...

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PID https://www.doi.org/10.6084/m9.figshare.c.3611174_d2
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Author Dalibor Breznan
Author Subramanian Karthikeyan
Author Marcelle Phaneuf
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Publication Date 2016-12-14
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Last Updated 14 January 2021, 13:14 (CET)
Created 14 January 2021, 13:14 (CET)