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Managing sequence-dependent setup times - The target conflict between output ...
Sequence-dependent setup times cause a trade-off between output rate, WIP and fluctuating throughput times. Companies usually face this trade-off by bundling similar orders in... -
Anxiety disorders and CRP in a population cohort study with 54326 participant...
Objectives – Growing evidence indicates that inflammatory processes may play a role in the pathogenesis of anxiety disorders. Nevertheless, much remains to be learned about the... -
The diagnostic accuracy of the hand-held Raman spectrometer for the identific...
Abstract Background There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to... -
Patients' preferences for involvement in the decision-making process for trea...
Abstract Background To assess factors associated with the preferred role of the attending ophthalmologist in the decision-making processes before treating diabetic retinopathy... -
Spirometric changes during exacerbations of COPD: a post hoc analysis of the ...
Abstract Background Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with loss of lung function and poor outcomes for patients. However, there are... -
The impairment of small nerve fibers in severe sepsis and septic shock
Abstract Background A decrease of small nerve fibers in skin biopsies during the course of critical illness has been demonstrated recently. However, the diagnostic use of skin... -
Homozygous TBC1 domain-containing kinase (TBCK) mutation causes a novel lysos...
Abstract Homozygous mutation of TBC1 domain-containing kinase (TBCK) is the cause of a very recently defined severe childhood disorder, which is characterized by severe... -
Optic-nerve-transmitted eyeshine, a new type of light emission from fish eyes
Abstract Background Most animal eyes feature an opaque pigmented eyecup to assure that light can enter from one direction only. We challenge this dogma by describing a... -
Suspicion of respiratory tract infection with multidrug-resistant Enterobacte...
Abstract Background Multidrug-resistant (MDR) infections are a serious concern for children admitted to the Paediatric Intensive Care Unit (PICU). Tracheal colonization with MDR... -
Local measles vaccination gaps in Germany and the role of vaccination providers
Abstract Background Measles elimination in Europe is an urgent public health goal, yet despite the efforts of its member states, vaccination gaps and outbreaks occur. This study... -
The role of employment interruptions and part-time work for the rise in wage ...
Abstract The incidence of employment interruptions and temporary part-time work has grown strongly among full-time workers, yet little is known about the impact on wage... -
Risk assessment of manual handling operations at work with the key indicator ...
Abstract Background Manual handling operations (MHO) are known to be risk factors for work-related upper limb disorders (WRULDs), e.g. symptoms and conditions such as carpal... -
Increasing the treatment motivation of patients with somatic symptom disorder...
Abstract Background Therapeutic intervention programs for somatic symptom disorder (SSD) show only small-to-moderate effect sizes. These effects are partly explained by the... -
Ancient coexistence of norepinephrine, tyramine, and octopamine signaling in ...
Abstract Background Norepinephrine/noradrenaline is a neurotransmitter implicated in arousal and other aspects of vertebrate behavior and physiology. In invertebrates,... -
Infection prevention and control measures and tools for the prevention of ent...
Abstract Background Infections with carbapenem-resistant Enterobacteriaceae (CRE) are increasingly being reported from patients in healthcare settings. They are associated with... -
Increased cortical activation upon painful stimulation in fibromyalgia syndrome
Abstract Background Fibromyalgia syndrome (FMS) is a chronic condition characterized by widespread pain and associated symptoms. We investigated cerebral activation in FMS... -
Nosological delineation of congenital ocular motor apraxia type Cogan: an obs...
Abstract Background The nosological assignment of congenital ocular motor apraxia type Cogan (COMA) is still controversial. While regarded as a distinct entity by some... -
Effects of cue modality and emotional category on recognition of nonverbal em...
Abstract Background Impaired interpretation of nonverbal emotional cues in patients with schizophrenia has been reported in several studies and a clinical relevance of these... -
Longitudinal estimation of Plasmodium falciparum prevalence in relation to ma...
Abstract Background Plasmodium falciparum prevalence (PfPR) is a widely used metric for assessing malaria transmission intensity. This study was carried out concurrently with... -
Demographics of patients receiving Intravitreal anti-VEGF treatment in real-w...
Abstract Background While randomized controlled trials (RCTs) are based on strict inclusion/exclusion criteria, non-interventional studies (NISs) might provide additional...