Chemokine release promotes cross-talk between opioid and chemokine receptors that in part leads to reduced efficacy of morphine in the treatment of chronic pain. On the basis of...

The synthesis, solution redox behavior, EPR, and intramolecular charge transfer properties of novel donor−acceptor diads of TTF−σ−A type (TTF = substituted tetrathiafulvalene, σ...

The first examples of monodisperse liquid crystalline pentamers, synthesized by covalently linking five mesogenic segments through four flexible spacers, exhibiting...

A macrocyclic receptor based on a bischromenylurea and an α,α‘-(o,o‘-dialkyl)diphenyl-p-xylylenediamine spacer provides a C2 chiral cavity to associate carboxylates by H-bonds....

A series of bis-iminonitroxide diradical derivatives of different lengths and geometry have been prepared that incorporate a conjugated phenylene-ethynylene bridge as a rigid...

A simple synthesis of dipolar one- and two-dimensional chromophores bearing two or three 4H-pyran-4-ylidene moieties is reported. Whereas the pyranylidene fragments acting as...

The design and synthesis of novel self-immolative spacer systems aiming at the release of phenol-containing compounds are described. The newly designed traceless linkers proved...

Arylhydrazones were linked onto gold nanoparticles through the poly(ethylene glycol) spacer to produce a new type of photoinduced DNA-cleaving nanomaterials with great potency.

: [figure: see text] A reliable and rigid spacer, trans,trans,trans-perhydronaphthacene, for molecular tweezers was designed. A synthesis and molecular recognition study of its...

Novel D-π-A NLO-phores based on the 1,3-dithiol-2-ylidene donor and the thiobarbituric acceptor moieties have been prepared. Modification of the length and rigidity of the...

New ionic liquid crystals (including ionic metallomesogens) based on the pyrrolidinium core are presented. N-Methylpyrrolidine was quaternized with different mesogenic groups...

Intramolecular electron transfer and exciplex formation have been investigated for a family of styrene−spacer−amine molecules in which the spacer consists of a rigid amide group...

Detailed results for comparing string-of-beads vaccines of different lengths with and without spacers. Detailed results for the comparison of string-of-beads with spacers and...