-
Elucidation of auxotrophic deficiencies of Bacillus pumilus DSM 18097 to deve...
Background Culture media containing complex compounds like yeast extract or peptone show numerous disadvantages. The chemical composition of the complex compounds is prone to... -
Module and individual domain deletions of NRPS to produce plipastatin derivat...
Background Plipastatin, an antifungal lipopeptide, is synthesized by a non-ribosomal peptide synthetase (NRPS) in Bacillus subtilis. However, little information is available on... -
PEGylated crushed gold shell-radiolabeled core nanoballs for in vivo tumor im...
Background Radioactive isotope-labeled gold nanomaterials have potential biomedical applications. Here, we report the synthesis and characterization of PEGylated crushed gold... -
Profilin 2 promotes migration, invasion, and stemness of HT29 human colorecta...
We investigated the role of profilin 2 in the stemness, migration, and invasion of HT29 cancer stem cells (CSCs). Increased and decreased levels of profilin 2 significantly... -
Ergothioneine production with Aspergillus oryzae
To establish a reliable and practical ergothioneine (ERG) supply, we employed fermentative ERG production using Aspergillus oryzae, a fungus used for food production. We... -
Structural analysis and taste evaluation of γ-glutamyl peptides comprising su...
The structures, flavor-modifying effects, and CaSR activities of γ-glutamyl peptides comprising sulfur-containing amino acids were investigated. The chemical structures,... -
Assessment of an anti-scale low-frequency electromagnetic field device on dri...
International audience; Low intensity and very low-frequency electromagnetic fields (EMF) used for preventing scaling in water distribution systems were tested for the first... -
Transcriptomes of a xylose-utilizing industrial flocculating Saccharomyces ce...
Lignocellulosic hydrolysates used for bioethanol production contain a mixture of sugars, with xylose being the second most abundant after glucose. Since xylose is not a natural... -
Chlorogenic acid ameliorates intestinal mitochondrial injury by increasing an...
Dietary polyphenols are thought to be beneficial for human health by acting as antioxidants. Chlorogenic acid (CGA) is abundant in plant-based foods as an ester of caffeic acid... -
The roles of the zinc finger transcription factors XlnR, ClrA and ClrB in the...
Genes encoding the key transcription factors (TF) XlnR, ClrA and ClrB were deleted from Aspergillus niger and the resulting strains were assessed for growth on glucose and wheat... -
Super-activator variants of the cyanobacterial transcriptional regulator ChlR...
ChlR is a MarR-type transcriptional regulator that activates the transcription of the chlAII-ho2-hemN operon in response to low oxygen conditions in the cyanobacterium... -
Effect of <i>O</i>-methylated and glucuronosylated flavonoids from <i>Tamarix...
O-Methylated and glucuronosylated flavonoids were isolated from Tamarix gallica as α-glucosidase inhibitors. Structure–activity relationship of these flavonoids suggests that... -
Down-regulation of senescence marker protein 30 by iron-specific chelator def...
To our knowledge, this is the first study to report down-regulation of senescence marker protein 30 (SMP30) by iron-specific chelator deferoxamine (DFO) on FAO cell senescence,... -
Activation of human bitter taste receptors by polymethoxylated flavonoids
Tangeretin and nobiletin are polymethoxylated flavonoids in citrus peel. Both tangeretin and nobiletin are bitter; however, their bitterness has not been evaluated using human... -
<i>Lactobacillus plantarum</i> LRCC 5273 isolated from Kimchi ameliorates die...
This study was designed to select potent cholesterol-lowering probiotic strains on HepG2 cell and investigate the effect of selected strain, Lactobacillus plantarum LRCC 5273... -
Enhanced L-cysteine production by overexpressing potential L-cysteine exporte...
We identified L-cysteine exporter candidates of Corynebacterium glutamicum and investigated the effect of overexpression of the potential L-cysteine exporter genes on L-cysteine... -
Global trends in research and commercialization of exogenous and endogenous R...
It has only been about 20 years since the first Nobel Prize-winning work on RNA interference (RNAi) in Caenorhabditis elegans was published in the journal Nature. Fast forward... -
Towards the development of a biobased economy in Europe and India
India has emerged as a key player with a high potential to develop a biomass and biobased economy due to its large geographic size and the massive amounts of agricultural and... -
A particular silent codon exchange in a recombinant gene greatly influences h...
Background Recombinant protein production using Escherichia coli as expression host is highly efficient, however, it also induces strong host cell metabolic burden. Energy and... -
Effect of light on carotenoid and lipid production in the oleaginous yeast <i...
The oleaginous yeast Rhodosporodium toruloides is receiving widespread attention as an alternative energy source for biofuels due to its unicellular nature, high growth rate and...
