85 items found

Tags: Methodology

Filter Results
  • dataset

    Building on shaky foundations? Lack of falsification and knowledge contestati...

    Among the defining characteristics of a healthy research discipline is the ability to correct its knowledge if more recent evidence creates grounds for this. Studies that reveal...
  • dataset

    Additional file 2: Figure S1. of Exploring how individuals complete the choic...

    Example of choice task rotavirus DCE, word document. Figure S2. Example of choice task prostate cancer-screening DCE, word document (ZIP 172 kb)
  • dataset

    Additional file 8: Table S3. of Effect of room temperature transport vials on...

    Primers and barcode sequences used in the study. (XLSX 13Â kb)
  • dataset

    Case-based research on democratization

    Empirical research on democratization is dominated by case studies and small-N comparisons. This article is a first attempt to take stock of qualitative case-based research on...
  • dataset

    Additional file 1 of Research methodology used in the 50 most cited articles ...

    Additional file 1. Supplementary file 1. Data for all characteristics of pediatrics’ citation classics that were analyzed within the study. The Excel table contains...
  • publication

    dedup_wf_001--e8e4f9dc39f84974c9d1edc1cd83afad

    Background DNA methylation at cytosine nucleotides constitutes epigenetic gene regulation impacting cellular development and a wide range of diseases. Cytosine bases of the DNA...
  • publication

    A minimal markerset for three-dimensional foot function assessment: measuring...

    Background The validity of predicting foot pronation occurring mainly at the midfoot by surrogate measures from the rearfoot, like eversion excursion, is limited. The dynamic...
  • publication

    Evaluations of the uptake and impact of the Preferred Reporting Items for Sys...

    Background The PRISMA Statement is a reporting guideline designed to improve transparency of systematic reviews (SRs) and meta-analyses. Seven extensions to the PRISMA Statement...
  • publication

    Post-trial follow-up methodology in large randomised controlled trials: a sys...

    Background Randomised controlled clinical trials typically have a relatively brief in-trial follow-up period which can underestimate safety signals and fail to detect long-term...
  • publication

    Meaningful engagement of people living with HIV who use drugs: methodology fo...

    Background Community-based HIV, harm reduction, and addiction research increasingly involve members of affected communities as Peer Research Associates (PRAs)—individuals with...
  • publication

    EpiMINE, a computational program for mining epigenomic data

    Background In epigenetic research, both the increasing ease of high-throughput sequencing and a greater interest in genome-wide studies have resulted in an exponential flooding...
  • publication

    Use of a modified GreenScreen tool to conduct a screening-level comparative h...

    Background Increased concern for potential health and environmental impacts of chemicals, including nanomaterials, in consumer products is driving demand for greater...
  • publication

    Algorithm and software to automatically identify latency and amplitude featur...

    Background Local field potentials (LFPs) evoked by sensory stimulation are particularly useful in electrophysiological research. For instance, spike timing and current...
  • publication

    Maternal blood contamination of collected cord blood can be identified using ...

    Background: Cord blood is a commonly used tissue in environmental, genetic, and epigenetic population studies due to its ready availability and potential to inform on a...
  • publication

    CONSORT-SPI 2018 Explanation and Elaboration: guidance for reporting social a...

    Background The CONSORT (Consolidated Standards of Reporting Trials) Statement was developed to help biomedical researchers report randomised controlled trials (RCTs)...
  • publication

    Methods of defining the non-inferiority margin in randomized, double-blind co...

    Background There is no consensus on the preferred method for defining the non-inferiority margin in non-inferiority trials, and previous studies showed that the rationale for...
  • publication

    MSP-HTPrimer: a high-throughput primer design tool to improve assay design fo...

    Background Bisulfite (BS) conversion-based and methylation-sensitive restriction enzyme (MSRE)-based PCR methods have been the most commonly used techniques for locus-specific...
  • publication

    A method for co-creation of an evidence-based patient workbook to address alc...

    The purpose of this paper is to describe a patient engagement event designed to create an educational workbook with smokers who drink alcohol at harmful levels. The goal was to...
  • publication

    Large-scale benchmarking reveals false discoveries and count transformation s...

    Background There is an immense scientific interest in the human microbiome and its effects on human physiology, health, and disease. A common approach for examining bacterial...
  • publication

    Freeze-drying: an alternative method for the analysis of volatile organic com...

    Background Volatile organic compounds (VOCs) can be intermediates of metabolic pathways and their levels in biological samples may provide a better understanding about diseases...