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r37980778c78--a40d986ef1025d19d9685143933b56e4
Using dendrimers in cancer therapy as nonviral vectors for gene delivery seems promising. The biological performance of a dendrimer-based gene delivery system depends heavily on... -
New Cannabidiol Derivatives: Synthesis, Binding to Cannabinoid Receptor, and...
Cannabidiol (CBD) and cannabidiol dimethyl hephtyl (CBD-DMH) were hydrogenated to give four different epimers. The new derivatives were evaluated for their ability to modulate... -
Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...
Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a... -
r37980778c78--65960e613b9f2af3dbb8122546d7d718
Necroptosis is a regulated caspase-independent cell death mechanism that can be induced in multiple cell types and is characterized by morphological features resembling... -
Development of a Novel Self-Microemulsifying Drug Delivery System for Reducin...
The development of HIV protease inhibitors (PIs) has been one of the most significant advances of the past decade in controlling HIV infection. Unfortunately, the benefits of... -
Metal-Mediated C−C Bond Making and Breaking: First Direct Evidence for a Rev...
Metal-Mediated C−C Bond Making and Breaking: First Direct Evidence for a Reversible Migration of a Benzyl Group along a Metal−Carbon Bond -
Additional file 8: of Mixture model normalization for non-targeted gas chroma...
Summary statistics for pairwise Spearman correlation among HAPO Metabolomics QC samples prior to and following normalization. Higher pairwise Spearman correlation indicates... -
dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7
A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary... -
r37980778c78--56fcee8741a21a8729fa2db393bd30b0
Design, synthesis, and in vitro bioevaluation of a new class of potential dual PPARα and γ agonists discovered through a structure-driven design paradigm are described. The... -
r37980778c78--5021c87261f3e825dde9a93ad9814f8e
To develop a novel antipsychotic agent which is an agonist of dopamine (DA) autoreceptors and an antagonist of postsynaptic DA receptors, a series of 7-[4-[4-(substituted... -
r37980778c78--20d5cb9ef2131f7c2f5fd1f5ab7c3f3a
The development of n-pentenyl furanosyl donors has been tested using arabinose as a model. The readily prepared ortho ester (NPOE) is converted into disarmed (NPGAC) and thence... -
Aryl Bridged 1-Hydroxypyridin-2-one: Effect of the Bridge on the Eu(III) Sens...
The efficiency of Eu3+ luminescence by energy transfer from an antenna ligand can be strongly dependent on the metal ion coordination geometry. The geometric component of the... -
Surfactant-Assisted Synthesis, Characterizations, and Catalytic Oxidation Mec...
A series of mesoporous MnOx−CeO2 binary oxide catalysts with high specific surface areas were prepared by surfactant-assisted precipitation. The CO and C3H8 oxidation reactions... -
Additional file 4 of A novel PET tracer 18F-deoxy-thiamine: synthesis, metabo...
Additional file 4: Figure 3B. B: HNMR result of precursor 5. -
r37980778c78--e669c313d8a9cdc92fd1159467d7eb1e
The derivatives of ethylenediamine-N,N,N‘,N‘-tetraamides were prepared, and their crystal structures were analyzed in order to understand the variations in their molecular and... -
MOESM1 of Circulating DNA as prognostic biomarker in patients with advanced h...
Additional file 1: Figure S1. Size distribution of extracted cfDNA after capillary electrophoresis (CE). DNA extracted from all the plasma samples were fractionated by CE and... -
Additional file 2: Figure S1. of Aberrant KDM5B expression promotes aggressiv...
Relative expression of KDM5B, MALAT1, SNAIL, Vimentin and miR 448 normalized against GAPDH in MCF10A WT, MCF10A OE, MDA-MB-231 WT and MDA-MB-231 KD cells. Data are... -
Design and Synthesis of 5‘-Deoxy-5‘-Phenyladenophostin A, a Highly Potent IP<...
5‘-Deoxy-5‘-phenyladenophostin A (5), designed as a useful IP3 receptor ligand based on the previous structure−activity relationship studies, was successfully synthesized via... -
r37980778c78--ae635c82dcc44980a276928de9b2909d
The first worldwide interlaboratory study on the analyses of 13 perfluorinated compounds (PFCs) in three environmental and two human samples indicates a varying degree of... -
dedup_wf_001--9767c68d06d859f6b9375220af68b101
Table. Anthropometry, body composition and biochemical data of women who underwent Roux in Y gastric bypass and normal weight controls. (DOCX 19 kb)
