5,022 items found

Licenses: License Not Specified Tags: Biochemistry Chemical Sciences not elsewhere classified Types: publication

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  • publication

    r37980778c78--a40d986ef1025d19d9685143933b56e4

    Using dendrimers in cancer therapy as nonviral vectors for gene delivery seems promising. The biological performance of a dendrimer-based gene delivery system depends heavily on...
  • publication

    Additional file 4: of Anti-aging potential of extracts from Sclerocarya birre...

    Negative mode BPI chromatogram of quinic acid pure standard overlaid with that of Marula stem ethanol extract. A comparison of the retention time of quinic acid pure standard...
  • publication

    r37980778c78--b83177d0c6de60e307794c8ade834f8e

    l-Fucose, 6-deoxy-l-galactose, is a key component of many important glycoconjugates including the blood group antigens and the LewisX ligands. The biosynthesis of GDP-l-fucose...
  • publication

    r37980778c78--a53b45f678a186371e2191f6aa1b0375

    Due to its function in the rate limiting initial step of the renin-angiotensin system, renin is a particularly promising target for drugs designed to control hypertension, a...
  • publication

    r37980778c78--088172a2a7cda9b5bc4673bb862e5a4a

    From the roots of Lespedeza cyrtobotrya, 45 flavonoids were isolated along with 20 new and 25 known compounds. Lipophilic flavonoids 2, 3, 7, 9, 11, 28, 30, and 39 exhibited...
  • publication

    New Cannabidiol Derivatives:  Synthesis, Binding to Cannabinoid Receptor, and...

    Cannabidiol (CBD) and cannabidiol dimethyl hephtyl (CBD-DMH) were hydrogenated to give four different epimers. The new derivatives were evaluated for their ability to modulate...
  • publication

    Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...

    Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a...
  • publication

    r37980778c78--7119beb953d143ed73039b17787f48f9

    This paper reviews in-use emissions from over-the-road heavy-duty (greater than 8500 lb gross vehicle weight) diesel vehicles. Emissions of particulate matter (PM), oxides of...
  • publication

    dedup_wf_001--6a72594ea900de3929241813a2954b20

    Lightning talk presented at Collaborations Workshop 2019 organised by the Software Sustainability Institute.
  • publication

    r37980778c78--fe9d5df9fcabf325d7c272ad16b6ed9f

    Chemical Alternatives Assessment: Enabling Substitution to Safer Chemicals
  • publication

    A Spray-Processable, Low Bandgap, and Ambipolar Donor−Acceptor Conjugated Pol...

    A Spray-Processable, Low Bandgap, and Ambipolar Donor−Acceptor Conjugated Polymer
  • publication

    Asymmetric Epoxidation of α-Olefins Having Neighboring Sugar Chiral Templates...

    Sugar-substituted epoxides 5−8 were synthesized by asymmetric epoxidation (in CH2Cl2/water) of α-olefins having neighboring sugars (1−4) by use of an achiral oxidant (MCPBA), in...
  • publication

    Evolving Carbapenemases: Can Medicinal Chemists Advance One Step Ahead of the...

    Carbapenems can be an effective treatment of infections with multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa,1 Acinetobacter spp.,2 Klebsiella...
  • publication

    Unregulated Emissions from a Heavy-Duty Diesel Engine with Various Fuels and ...

    This study evaluated the effects of various combinations of fuels and emission control technologies on exhaust emissions from a heavy-duty diesel engine tested on an engine...
  • publication

    r37980778c78--1432abdeb57253465dd8e782cca54e4b

    A fluorescent deoxyuridine analogue is sensitive to the polarity of its environment and exhibits a distinct emission profile in single- vs double-stranded oligonucleotides....
  • publication

    r37980778c78--65960e613b9f2af3dbb8122546d7d718

    Necroptosis is a regulated caspase-independent cell death mechanism that can be induced in multiple cell types and is characterized by morphological features resembling...
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    Stereochemical Features of the Physical and Chemical Interactions of Singlet ...

    Oxazolidinone-substituted enecarbamates represent a mechanistically rich system for the study of stereoelectronic, steric, and conformational effects on stereoselectivity and...
  • publication

    Development of a Novel Self-Microemulsifying Drug Delivery System for Reducin...

    The development of HIV protease inhibitors (PIs) has been one of the most significant advances of the past decade in controlling HIV infection. Unfortunately, the benefits of...
  • publication

    Metal-Mediated C−C Bond Making and Breaking:  First Direct Evidence for a Rev...

    Metal-Mediated C−C Bond Making and Breaking:  First Direct Evidence for a Reversible Migration of a Benzyl Group along a Metal−Carbon Bond
  • publication

    dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7

    A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary...