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Economic evaluation of nivolumab combined with ipilimumab in the first-line t...
The objective of this study was to evaluate the cost-effectiveness of nivolumab in combination with ipilimumab (nivo + ipi) compared to current therapeutic alternatives in... -
Pricing methods in outcome-based contracting: δ2: Willingness-to-pay-based pr...
Aims: Six Delta is a six-dimensional independent platform for outcome-based pricing/contracting. The second dimension (δ2) estimates prices on the basis of four... -
Spatial modelling of cumulative human pressure in the tropical coastscape of ...
Coastal landscapes and seascapes (‘coastscapes’) are under immense anthropogenic pressures emanating from multiple human activities. We applied spatial modelling to characterise... -
Medication therapy strategies for the coronavirus disease 2019 (COVID-19): re...
The coronavirus disease 2019 (COVID-19) pandemic has spread globally since it outbroke in December 2019. The urgent pandemic presents an unprecedented challenge to develop and... -
The economic burden of common adverse events associated with metastatic color...
Aims: Adverse events (AEs) associated with treatments for metastatic colorectal cancer (mCRC) may compromise the course of treatment, impact quality-of-life, and increase... -
dedup_wf_001--7e8c64fe8aec89e996dbca4bb012f2b4
Occupation-based practice involves the inclusion of meaningful occupations in the therapeutic process and is promoted within hospital-based general rehabilitation contexts for... -
Systematic literature review of the epidemiology and clinical burden of chron...
We conducted a systematic literature review (SLR) to determine the epidemiology and clinical burden of chronic rhinosinusitis with nasal polyps (CRSwNP) and to describe how the... -
Eye Injuries and Related Risk Factors among Workers in Small-scale Industrial...
PURPOSE We aimed to study eye injuries and their risk factors among workers at small-scale industrial enterprises. METHODS Cross-sectional descriptive study. Five hundred... -
Cost per responder analysis of guselkumab versus targeted therapies in the tr...
BACKGROUND The fully human monoclonal antibody guselkumab is an effective treatment option for patients with moderate to severe psoriasis. OBJECTIVE The objective of this study... -
A scoping review of psychoeducational interventions for people after transien...
Psychoeducation can provide information and support to cope with the physical and emotional effects of a health condition. This scoping review aimed to identify the evidence... -
dedup_wf_001--d5ebcd7f48b176b196d0987797f77b18
Broadband policy has been booming with the support of European Structural and Investment Funds (ESIFs). However, its performance and impact remain contentious, since primary... -
Renal complications in COVID-19: a systematic review and meta-analysis
Emerging data suggest that coronavirus disease 2019 (COVID-19) has extrapulmonary manifestations but its renal manifestations are not clearly defined. We aimed to evaluate renal... -
Vehicle safety characteristics in vulnerable driver populations
National data suggest drivers who are younger, older, and have lower socioeconomic status (SES) have heightened crash-related injury rates. Ensuring vulnerable drivers are in... -
dedup_wf_001--b2aea697ee420d2a6a886a8155e8b204
The β-D-Mannuronic acid (M2000) as a novel immunosuppressive drug, patented (PCT/EP2017/067920), has shown positive effects in experimental model of multiple sclerosis (MS). In... -
Drug development for noise-induced hearing loss
[Introduction] Excessive exposure to noise is a common occurrence that contributes to approximately 50% of the non-genetic hearing loss cases. Researchers need to develop... -
Respiratory depression following medications for opioid use disorder (MOUD)-a...
Medications for opioid use disorder (MOUD) including buprenorphine is recommended for patients with opioid use disorders. We sought to evaluate the frequencies of respiratory... -
Potential Precursor of Angiotensin-I Converting Enzyme (ACE) Inhibitory Activ...
Peptic hydrolysates were prepared by digesting the cutlassfish muscle protein using pepsin for 1, 3, and 6 h, and their inhibitory activity against angiotensin-I converting... -
Genetic factors in anthracycline-induced cardiotoxicity in patients treated f...
Cardiovascular diseases are the main cause of treatment-related morbidity and mortality in childhood cancer patients. Anthracyclines, one of the most common chemotherapeutic... -
Verification of the hemolysis index measurement: imprecision, accuracy, measu...
Automated spectrophotometric measurement of hemolysis index (HI) allows rapid and cost-effective assessment of hemolysis interference. We evaluated the analytical performance of... -
Cost utility analysis of tisagenlecleucel vs salvage chemotherapy in the trea...
Background: Patients with relapsed or refractory diffuse large B-cell lymphoma (r/r DLBCL) have limited treatment options and poor prognoses. Tisagenlecleucel, a chimeric...
