Drug development for noise-induced hearing loss
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http://data.d4science.org/ctlg/RISIS2OpenData/dedup_wf_001--3b37d7a00f56574fbd74ed3ff5809933 |
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Identity
Access Modality
Field | Value |
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Access Right | Restricted |
Attribution
Field | Value |
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Author | Varela-Nieto, Isabel |
Author | Murillo-Cuesta, Silvia |
Author | Calvino, Miryam |
Author | Cediel, Rafael |
Author | Lassaletta, Luis |
Contributor | European Commission |
Contributor | Comunidad de Madrid |
Contributor | Ministerio de Ciencia, Innovación y Universidades (España) |
Contributor | Agencia Estatal de Investigación (España) |
Publishing
Field | Value |
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Collected From | Digital.CSIC; Datacite; figshare; Crossref |
Hosted By | Digital.CSIC; Expert Opinion on Drug Discovery; figshare |
Publication Date | 2020-08-25 |
Publisher | Taylor & Francis |
Additional Info
Field | Value |
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Country | Spain |
Description | [Areas covered] In this review, the authors discuss the many facets of human noise-induced pathology, and the primary experimental models for studying the basic mechanisms of noise-induced damage, making connections and inferences among basic science studies, preclinical proofs of concept and clinical trials. |
Description | [Expert opinion] Whilst experimental research in animal models has helped to unravel the mechanisms of noise-induced hearing loss, there are often methodological variations and conflicting results between animal and human studies which make it difficult to integrate data and translate basic outcomes to clinical practice. Standardization of exposure paradigms and application of -omic technologies will contribute to improving the effectiveness of transferring newly gained knowledge to clinical practice. |
Description | This work was supported by the grants Multi Target and View FEDER/CM-B2017/BMD-3688 from the Consejería de Educación e Investigación, Comunidad de Madrid and MINECO/FEDER SAF2017-86107-R from the Ministerio de Economía, Industria y Competitividad, Gobierno de España. |
Description | Peer reviewed |
Language | UNKNOWN |
Resource Type | Other literature type; Article |
keyword | FOS: Health sciences |
keyword | FOS: Biological sciences |
system:type | publication |
Management Info
Field | Value |
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Source | https://science-innovation-policy.openaire.eu/search/publication?articleId=dedup_wf_001::3b37d7a00f56574fbd74ed3ff5809933 |
Author | jsonws_user |
Last Updated | 25 December 2020, 18:14 (CET) |
Created | 25 December 2020, 18:14 (CET) |