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Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organi...
Abstract Background Stem cell senescence has been proposed as one of the major drivers of aging, and MSC senescence contributes to aging-related diseases. Activation of mTORC1... -
dedup_wf_001--678de25d4a66913eeaf6f1bd36b33ffe
Additional file 1. Representative standard curve and amplification plot from each let-7 family member RT-qPCR. Standard curve and amplification plot from (A) let-7a, (B) let-7b,... -
A metagenomic study of the gut microbiome in Behcet’s disease
Abstract Background Behcet’s disease (BD) is a recalcitrant, multisystemic inflammatory disease that can lead to irreversible blindness. Microbial agents have been considered to... -
Waist circumference is associated with major adverse cardiovascular events in...
Abstract Background Although studies have shown that waist circumference (WC) is positively associated with an increased risk of cardiovascular diseases among the normal... -
Additional file 6: Figure S5. of Development of an integrated approach for co...
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) (A), interleukin (IL)-1α (B), IL-1β (C), IL-5 (D), IL-10 (E), Keratinocyte-derived Chemokine (KC) (F), Macrophage... -
Associations among left ventricular systolic function, tachycardia, and cardi...
Abstract Background In sepsis, tachycardia may indicate low preload, adrenergic stimulation, or both. Adrenergic overstimulation is associated with septic cardiomyopathy. We... -
The Red Queen in the Repository: metadata quality in an ever-changing environ...
This fileset contains a preprint version of the conference paper (.pdf), presentation slides (as .pptx) and the dataset(s) and validation schema(s) for the IDCC 2019 (Melbourne)... -
Study dataset.
Compliance with NPG checklist items: data dictionary available in project space. In version 2, 7 errors from the previous version at database lock (publication date for PMID... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated... -
TRPV1 mediates astrocyte activation and interleukin-1β release induced by hyp...
Abstract Background Hypoxic-ischemic encephalopathy (HIE) is a serious birth complication with high incidence in both advanced and developing countries. Children surviving from... -
Additional file 2 of Metabolic characterization of aggressive breast cancer c...
Additional file 2: Supplemental Figure 2. Mitochondrial membrane potential of SUM149 invading cells. -
Additional file 1 of Impact of malnutrition on systemic immune and metabolic ...
Additional file 1: Figure S1. Flowchart for the study participant recruitment. A flowchart illustrating participant recruitment to the study. -
Increased circulating microRNA-122 is associated with mortality and acute liv...
Abstract Background Acute liver injury in patients with ARDS decreases survival but early stages may be easily missed due to the lack of sufficient biomarkers signalling its... -
The human fetal adrenal produces cortisol but no detectable aldosterone throu...
Abstract Background Human fetal adrenal glands are highly active and, with the placenta, regulate circulating progesterone, estrogen and corticosteroids in the fetus. At birth... -
Circulating microRNA-92a level predicts acute coronary syndrome in diabetic p...
Abstract Purpose This study was designed to explore the value of monitoring miR-92a in T2DM patients with coronary heart disease (CHD). Materials and methods 40 ACS patients... -
Single nucleotide polymorphisms in apoptosis pathway are associated with resp...
Abstract Background The mechanism of action of imatinib is known to involve the Fas-mediated apoptosis pathway. Consequently inter-individual variations in this apoptosis... -
AgMIP's Global Gridded Crop Model Intercomparison (GGCMI) phase 1 output data...
This is model output from GEPIC for rice as part of AgMIP's Global Gridded Crop Model Intercomparison (GGCMI) phase 1 output data set. The data have been generated... -
Prevalence and profile of adverse drug reactions in high-risk pregnancy: a co...
Abstract Background Commonly used drugs in pregnant women include antihypertensives, hypoglycemic agents, analgesics, antimicrobials, antiemetics and antispasmodics but the use... -
Murine host response to Neisseria gonorrhoeae upper genital tract infection r...
Abstract Background The emergence of fully antimicrobial resistant Neisseria gonorrhoeae has led global public health agencies to identify a critical need for next generation...
