a: No further information was identified in results registries of manufacturers.b: The designation of the primary outcome in the SR does not necessarily correspond to the operationalization of this outcome in the trials included in the systematic review (outcome in the trial included in the SR: recurrence of any affective episode; listed in Table 3).c: If information on clinical outcomes was unavailable, the SR considered surrogate outcomes.CGI: clinical global impression; HAM-D: Hamilton rating scale for depression; LDL-C: low-density lipoprotein cholesterol; MADRS: Montgomery–Åsberg Depression Rating Scale; SR: systematic review.