Integrating text mining, data mining, and network analysis for identifying genetic breast cancer trends

Background Breast cancer is a serious disease which affects many women and may lead to death. It has received considerable attention from the research community. Thus, biomedical researchers aim to find genetic biomarkers indicative of the disease. Novel biomarkers can be elucidated from the existing literature. However, the vast amount of scientific publications on breast cancer make this a daunting task. This paper presents a framework which investigates existing literature data for informative discoveries. It integrates text mining and social network analysis in order to identify new potential biomarkers for breast cancer. Results We utilized PubMed for the testing. We investigated gene–gene interactions, as well as novel interactions such as gene-year, gene-country, and abstract-country to find out how the discoveries varied over time and how overlapping/diverse are the discoveries and the interest of various research groups in different countries. Conclusions Interesting trends have been identified and discussed, e.g., different genes are highlighted in relationship to different countries though the various genes were found to share functionality. Some text analysis based results have been validated against results from other tools that predict gene–gene relations and gene functions. Electronic supplementary material The online version of this article (doi:10.1186/s13104-016-2023-5) contains supplementary material, which is available to authorized users.

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PID https://www.doi.org/10.1186/s13104-016-2023-5
PID pmc:PMC4845430
PID pmid:27112211
URL https://bmcresnotes.biomedcentral.com/track/pdf/10.1186/s13104-016-2023-5
URL https://www.ncbi.nlm.nih.gov/pubmed/27112211
URL https://core.ac.uk/display/81898590
URL https://dx.doi.org/10.1186/s13104-016-2023-5
URL http://hdl.handle.net/20.500.11851/2040
URL http://dx.doi.org/10.1186/s13104-016-2023-5
URL https://doi.org/10.1186/s13104-016-2023-5
URL https://academic.microsoft.com/#/detail/2344996561
URL http://europepmc.org/articles/PMC4845430
URL https://link.springer.com/article/10.1186/s13104-016-2023-5
URL https://paperity.org/p/77119450/integrating-text-mining-data-mining-and-network-analysis-for-identifying-genetic-breast
URL https://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-016-2023-5
URL http://link.springer.com/content/pdf/10.1186/s13104-016-2023-5
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Access Right Open Access
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Author Jurca, G.
Author  Addam, O.
Author  Aksac, A.
Author Gao,S.
Author Özyer, Tansel
Author  Demetrick, D.
Author  Alhajj, R.
Contributor TOBB ETU, Faculty of Engineering, Department of Computer Engineering
Contributor TOBB ETÜ, Mühendislik Fakültesi, Bilgisayar Mühendisliği Bölümü
Contributor Özyer, Tansel
Contributor 143116
Contributor 8914139000
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Collected From Europe PubMed Central; OpenAPC Initiative; PubMed Central; Datacite; UnpayWall; TOBB ETÜ Institutional Repository; Crossref; Microsoft Academic Graph; CORE (RIOXX-UK Aggregator)
Hosted By Europe PubMed Central; OpenAPC Initiative; SpringerOpen; BMC Research Notes; TOBB ETÜ Institutional Repository
Journal BMC Research Notes, 9,
Publication Date 2016-04-26
Publisher BioMed Central
Additional Info
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Country Turkey
Format application/pdf
Language English
Resource Type Other literature type; Conference object; Article; UNKNOWN
keyword Biochemistry, Genetics and Molecular Biology_all_
keyword Data Mining 
keyword  Extraction 
keyword  manual curation
system:type publication
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Source https://science-innovation-policy.openaire.eu/search/publication?articleId=dedup_wf_001::efe8a3329ce2be85ce538021705b979c
Author jsonws_user
Last Updated 22 December 2020, 23:20 (CET)
Created 22 December 2020, 23:20 (CET)