Total Synthesis of Apratoxin A

Apratoxin A, a cyclodepsipeptide isolated from cyanobacterial Lyngbya spp, has been synthesized. The total synthesis features stereocontrolled access to the novel polyketide and the late-stage installation of the sensitive 2,4-disubstituted thiazoline moiety using an intramolecular Staudinger reduction/aza-Wittig process.

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PID https://www.doi.org/10.1021/ja036050w.s001
PID https://www.doi.org/10.1021/ja036050w
PID https://www.doi.org/10.1021/ja036050w.s002
URL http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100534972
URL https://figshare.com/articles/journal_contribution/Total_Synthesis_of_Apratoxin_A/3652446
URL http://dx.doi.org/10.1021/ja036050w
URL https://academic.microsoft.com/#/detail/2078480858
URL https://www.ncbi.nlm.nih.gov/pubmed/12862462
URL https://pubmed.ncbi.nlm.nih.gov/12862462/
URL https://pubs.acs.org/doi/pdf/10.1021/ja036050w
URL http://pubs.acs.org/doi/abs/10.1021/ol052907d
URL https://pubs.acs.org/doi/10.1021/ol052907d
URL https://figshare.com/articles/journal_contribution/Total_Synthesis_of_Apratoxin_A/3652440
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Access Right Open Access
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Author Chen, Jiehao
Author Forsyth, Craig J.
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Collected From figshare; Crossref; Microsoft Academic Graph; JAIRO
Hosted By Journal of the American Chemical Society; figshare; JAIRO
Publication Date 2016-08-18
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Language English
Resource Type Other literature type; Conference object; Article
system:type publication
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Source https://science-innovation-policy.openaire.eu/search/publication?articleId=dedup_wf_001::880ed098afac91cb1dd9ec033f4e6f76
Author jsonws_user
Last Updated 25 December 2020, 10:29 (CET)
Created 25 December 2020, 10:29 (CET)