1,028 items found

Types: publication Tags: Biochemistry Biotechnology Cancer

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  • publication

    r37980778c78--a53b45f678a186371e2191f6aa1b0375

    Due to its function in the rate limiting initial step of the renin-angiotensin system, renin is a particularly promising target for drugs designed to control hypertension, a...
  • publication

    Metal-Mediated C−C Bond Making and Breaking:  First Direct Evidence for a Rev...

    Metal-Mediated C−C Bond Making and Breaking:  First Direct Evidence for a Reversible Migration of a Benzyl Group along a Metal−Carbon Bond
  • publication

    dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7

    A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary...
  • publication

    r37980778c78--6694cef58c3bedccedb2229ef5cea82e

    Different virtual screening techniques are available as alternatives to high throughput screening. These different techniques have been rarely used together on the same target....
  • publication

    MOESM1 of Circulating DNA as prognostic biomarker in patients with advanced h...

    Additional file 1: Figure S1. Size distribution of extracted cfDNA after capillary electrophoresis (CE). DNA extracted from all the plasma samples were fractionated by CE and...
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    Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (...

    A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and...
  • publication

    In vitro and In vivo Optical Imaging Using Water-Dispersible, Noncytotoxic, L...

    A facile method for synthesis of monodisperse, biocompatible, silica coated CdSe/CdS/ZnS quantum rods (QRs) and their use as probes for in vitro and in vivo optical bioimaging...
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    Direct Thioepoxidation of Strained Cyclic Alkenes by the Photolytic Sulfur-At...

    Direct Thioepoxidation of Strained Cyclic Alkenes by the Photolytic Sulfur-Atom Transfer from Thiocarbonyl S-Oxides (Sulfines)
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    Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydr...

    A series of 3-descladinosyl-2,3-anhydro-6-O-methylerythromycin A 11,12-carbamate analogues have been synthesized and evaluated for antibacterial activity. These compounds were...
  • publication

    Integrated Comparison of Drug-Related and Drug-Induced Ultra Performance Liqu...

    The biochemical variations induced in human primary hepatocyte cultures by reference activators of xenoreceptor CAR (NR1I3) and PXR (NR1I2), i.e., rifampicin, phenobarbital, and...
  • publication

    dedup_wf_001--30988551625bdfa693abdf9f8b77535c

    Additional file 1: Figure S1. Effect of culture conditions on cellulase production from Cellulomonas bogoriensis. (a) Effect of carbon source on cellulase production; (b) Effect...
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    Identification of a Boron-Containing Intermediate in the Boron Tribromide Med...

    An alternate reaction mechanism for the boron tribromide mediated deprotection of aryl propargyl ethers based on the isolation of a key boron-containing byproduct is proposed....
  • publication

    r37980778c78--171b2989a7b99d872f8aab415bba7cb6

    A new and promising group of antibacterial agents, collectively known as the oxazolidinones and exemplified by linezolid (PNU-100766, marketed as Zyvox), have recently emerged...
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    Intramolecular Cycloadditions between Cyclobutadiene and Alkenes

    Intramolecular Cycloadditions between Cyclobutadiene and Alkenes
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    Hepatic CYP1A Induction by Chlorinated Dioxins and Related Compounds in the E...

    The present study assesses effects of dioxins and related compounds (DRCs) including polychlorinated dibenzo-p-dioxins, polychlorinated dibenzofurans, and dioxin-like...
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    Platinum(II)-Catalyzed Intermolecular [3 + 2] Cycloaddition of Propadienyl Si...

    A Pt(II)-catalyzed [3 + 2] cycloaddition reaction of silyl propadienyl ethers and alkenyl ethers has been developed as the first example of the utilization of allenes as a...
  • publication

    Additional file 1: Tables S1-S3. of Endocrine and exocrine pancreatic insuffi...

    Comparision on the disease severity, complication and pancreatic necrosis between NGT, IGT and DM groups. The APACHE II score and Balthazar score in group DM was significant...
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    Highly Luminescent, Triple- and Quadruple-Stranded, Dinuclear Eu, Nd, and Sm(...

    The bis(β-diketone) ligands 1,3-bis(3-phenyl-3-oxopropanoyl)benzene, H2L1 and 1,3-bis(3-phenyl-3-oxopropanoyl) 5-ethoxy-benzene, H2L2, have been prepared for the examination of...
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    Life Cycle Assessment and Grid Electricity: What Do We Know and What Can We K...

    The generation and distribution of electricity comprises nearly 40% of U.S. CO2 emissions, as well as large shares of SO2, NOx, small particulates, and other toxins. Thus,...