4,843 items found

Tags: Genetics Cancer Molecular Biology

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  • dataset

    Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organi...

    Abstract Background Stem cell senescence has been proposed as one of the major drivers of aging, and MSC senescence contributes to aging-related diseases. Activation of mTORC1...
  • dataset

    Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D...

    Many chemotherapeutic drugs cause nucleolar stress and p53-independent pathways mediating the nucleolar stress response are emerging. Here, we demonstrate that ribosomal stress...
  • dataset

    PathoPhenoDB: a database of pathogen-phenotype associations

    PathoPhenoDB is a database containing pathogen-to-phenotype associations mined from the scientific literature. PathoPhenoDB relies on manual curation of pathogen-disease...
  • dataset

    Additional file 1: of PHD-finger domain protein 5A functions as a novel oncop...

    Table S1. The primers used for qRT-PCR analysis. (DOC 35 kb)
  • dataset

    dedup_wf_001--678de25d4a66913eeaf6f1bd36b33ffe

    Additional file 1. Representative standard curve and amplification plot from each let-7 family member RT-qPCR. Standard curve and amplification plot from (A) let-7a, (B) let-7b,...
  • dataset

    A family of auxin conjugate hydrolases from Solanum lycopersicum and analysis...

    Abstract Background Auxin conjugates are hydrolyzed to release free auxin to ensure defined cellular auxin levels or gradients within tissues for proper development or response...
  • dataset

    Database of mechanism of action paths for selected drug-disease indications

    Mechanistic paths that lead from drug to disease in a heterogeneous network. Version 1.1.0 includes a new tab metapaths_biolink where the majority of node and edge types have...
  • dataset

    Landscape of gene fusions in epithelial cancers: seq and ye shall find

    Abstract Enabled by high-throughput sequencing approaches, epithelial cancers across a range of tissue types are seen to harbor gene fusions as integral to their landscape of...
  • dataset

    First DNA evidence on the occurrence of Pacific bluefin tuna, Thunnus orienta...

    Abstract Background Pacific bluefin tuna (Thunnus orientalis) spawning adults, juveniles and larvae are all reported to occur in areas between Philippine Sea and Japan Sea....
  • dataset

    pTuneos: prioritizing tumor neoantigens from next-generation sequencing data

    Abstract Background Cancer neoantigens are expressed only in cancer cells and presented on the tumor cell surface in complex with major histocompatibility complex (MHC) class I...
  • dataset

    Evaluation of folate receptor 1 (FOLR1) mRNA expression, its specific promote...

    Abstract Background In this retrospective study we evaluated the respective correlations and clinical relevance of FOLR1 mRNA expression, FOLR1 promoter specific methylation and...
  • dataset

    Additional file 18: Table S10. of Extracting a low-dimensional description of...

    The enrichment of the marker modules that were selected by the Significance Analysis of Microarrays (SAM) procedure to be significantly differentially expressed in one of the...
  • dataset

    dedup_wf_001--03bbe3d4eb4587078a3a697b4d898888

    Genes with up-regulated expression found in samples derived from cow mammary gland parenchyma infected with coagulase-positive Staphylococci in 3rd or 4th lactations (CoPS-3/4)....
  • dataset

    Differential DNA methylation marks and gene comethylation of COPD in African-...

    Abstract Background Chronic obstructive pulmonary disease (COPD) is the third-leading cause of death worldwide. Identifying COPD-associated DNA methylation marks in...
  • dataset

    Main SNP file STRUCTURE format

    Dataset of 3764 SNP structure file. Population information included in second column.
  • dataset

    Eisenhauer et al 2017 Sci Rep Data

    Eisenhauer et al 2017 Sci Rep Data
  • dataset

    Pirfenidone attenuates lung fibrotic fibroblast responses to transforming gro...

    Abstract Background Pirfenidone, an antifibrotic agent used for the treatment of idiopathic pulmonary fibrosis (IPF), functions by inhibiting myofibroblast differentiation,...
  • dataset

    An integrated framework for the identification of potential miRNA-disease ass...

    MicroRNAs (miRNAs) play an important role in prevention, diagnosis and treatment of human complex diseases. Predicting potential miRNA-disease associations could provide...
  • dataset

    ModelSel_HAFL_2013_Occupancy

    AIC model selection table and associated coefficients for Hammond’s flycatcher 2013 for all initial occupancy models. Column names for the model coefficients use the following...