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Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organi...
Abstract Background Stem cell senescence has been proposed as one of the major drivers of aging, and MSC senescence contributes to aging-related diseases. Activation of mTORC1... -
Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D...
Many chemotherapeutic drugs cause nucleolar stress and p53-independent pathways mediating the nucleolar stress response are emerging. Here, we demonstrate that ribosomal stress... -
dedup_wf_001--678de25d4a66913eeaf6f1bd36b33ffe
Additional file 1. Representative standard curve and amplification plot from each let-7 family member RT-qPCR. Standard curve and amplification plot from (A) let-7a, (B) let-7b,... -
Association of Modic change types and their short tau inversion recovery sign...
Abstract Background Modic Changes (MCs, magnetic resonance imaging (MRI) signal changes in the vertebral bone marrow extending from the vertebral endplate) may represent a... -
A family of auxin conjugate hydrolases from Solanum lycopersicum and analysis...
Abstract Background Auxin conjugates are hydrolyzed to release free auxin to ensure defined cellular auxin levels or gradients within tissues for proper development or response... -
Mouse data
Counts of adults worms and miracidea of 3 different lines (susceptible, resistant and mixed resistant-susceptible) inside the mouse host exposed to three different treatments:... -
Selection experiment data
This file contains adult survival data and juvenile population counts during the course of the selection experiment described in the associated publication. The proportion of... -
Additional file 18: Table S10. of Extracting a low-dimensional description of...
The enrichment of the marker modules that were selected by the Significance Analysis of Microarrays (SAM) procedure to be significantly differentially expressed in one of the... -
Additional file 1: Figure S1. of Low oxygen tension reverses antineoplastic e...
Phase-contrast microscopy photography of U251 and U87 glioblastoma cells cultivated at 21 % or 3 % of oxygen in non-treated condition (CONT) or 3 days after treatment with 5 μM... -
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming gro...
Abstract Background Pirfenidone, an antifibrotic agent used for the treatment of idiopathic pulmonary fibrosis (IPF), functions by inhibiting myofibroblast differentiation,... -
Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis prog...
Abstract Background SIRT1 histone deacetylase acts on many epigenetic and non-epigenetic targets. It is thought that SIRT1 is involved in oocyte maturation; therefore, the... -
The Red Queen in the Repository: metadata quality in an ever-changing environ...
This fileset contains a preprint version of the conference paper (.pdf), presentation slides (as .pptx) and the dataset(s) and validation schema(s) for the IDCC 2019 (Melbourne)... -
Additional file 3: of Stillbirth surveillance and review in rural districts i...
Frequency of ante and intrapartum complications among mothers who experienced a stillbirth for all stillbirths combined, fresh stillbirths and macerated stillbirths (nâ =â... -
Study dataset.
Compliance with NPG checklist items: data dictionary available in project space. In version 2, 7 errors from the previous version at database lock (publication date for PMID... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated... -
TRPV1 mediates astrocyte activation and interleukin-1β release induced by hyp...
Abstract Background Hypoxic-ischemic encephalopathy (HIE) is a serious birth complication with high incidence in both advanced and developing countries. Children surviving from... -
Additional file 2 of Metabolic characterization of aggressive breast cancer c...
Additional file 2: Supplemental Figure 2. Mitochondrial membrane potential of SUM149 invading cells. -
Additional file 1 of Impact of malnutrition on systemic immune and metabolic ...
Additional file 1: Figure S1. Flowchart for the study participant recruitment. A flowchart illustrating participant recruitment to the study.