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Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organi...
Abstract Background Stem cell senescence has been proposed as one of the major drivers of aging, and MSC senescence contributes to aging-related diseases. Activation of mTORC1... -
Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D...
Many chemotherapeutic drugs cause nucleolar stress and p53-independent pathways mediating the nucleolar stress response are emerging. Here, we demonstrate that ribosomal stress... -
KRAS_10-2_144148_filtered.csv
A gzipped csv documenting the tag, read sequence, and associated qualities of all reads matching the majority read length (documented in read lengths csv) of gDNA 10^-2 sample,... -
dedup_wf_001--678de25d4a66913eeaf6f1bd36b33ffe
Additional file 1. Representative standard curve and amplification plot from each let-7 family member RT-qPCR. Standard curve and amplification plot from (A) let-7a, (B) let-7b,... -
Association of Modic change types and their short tau inversion recovery sign...
Abstract Background Modic Changes (MCs, magnetic resonance imaging (MRI) signal changes in the vertebral bone marrow extending from the vertebral endplate) may represent a... -
A family of auxin conjugate hydrolases from Solanum lycopersicum and analysis...
Abstract Background Auxin conjugates are hydrolyzed to release free auxin to ensure defined cellular auxin levels or gradients within tissues for proper development or response... -
Landscape of gene fusions in epithelial cancers: seq and ye shall find
Abstract Enabled by high-throughput sequencing approaches, epithelial cancers across a range of tissue types are seen to harbor gene fusions as integral to their landscape of... -
Pharmacological pain relief and fear of childbirth in low risk women; seconda...
Abstract Background Fear of childbirth may reduce the womens’ pain tolerance during labour and may have impact on the mother-infant interaction. We aimed to assess (1) the... -
Comparison of DNA quantification methodology used in the DNA extraction proto...
Abstract Background UK Biobank is a large prospective cohort study in the UK established by the Medical Research Council (MRC) and the Wellcome Trust to enable approved... -
Mouse data
Counts of adults worms and miracidea of 3 different lines (susceptible, resistant and mixed resistant-susceptible) inside the mouse host exposed to three different treatments:... -
Evaluation of folate receptor 1 (FOLR1) mRNA expression, its specific promote...
Abstract Background In this retrospective study we evaluated the respective correlations and clinical relevance of FOLR1 mRNA expression, FOLR1 promoter specific methylation and... -
Additional file 18: Table S10. of Extracting a low-dimensional description of...
The enrichment of the marker modules that were selected by the Significance Analysis of Microarrays (SAM) procedure to be significantly differentially expressed in one of the... -
Additional file 1: of Factors related with colorectal and stomach cancer scre...
Questionnaires about uptake of gastrointestinal cancer screening among lung cancer survivors. (DOCX 14Â kb) -
Additional file 6: Figure S5. of Development of an integrated approach for co...
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) (A), interleukin (IL)-1α (B), IL-1β (C), IL-5 (D), IL-10 (E), Keratinocyte-derived Chemokine (KC) (F), Macrophage... -
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming gro...
Abstract Background Pirfenidone, an antifibrotic agent used for the treatment of idiopathic pulmonary fibrosis (IPF), functions by inhibiting myofibroblast differentiation,... -
Epigenetic and non-epigenetic mode of SIRT1 action during oocyte meiosis prog...
Abstract Background SIRT1 histone deacetylase acts on many epigenetic and non-epigenetic targets. It is thought that SIRT1 is involved in oocyte maturation; therefore, the... -
The Red Queen in the Repository: metadata quality in an ever-changing environ...
This fileset contains a preprint version of the conference paper (.pdf), presentation slides (as .pptx) and the dataset(s) and validation schema(s) for the IDCC 2019 (Melbourne)... -
Study dataset.
Compliance with NPG checklist items: data dictionary available in project space. In version 2, 7 errors from the previous version at database lock (publication date for PMID... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated...
