3,330 items found

Tags: Computational Biology Pharmacology

Filter Results
  • dataset

    Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D...

    Many chemotherapeutic drugs cause nucleolar stress and p53-independent pathways mediating the nucleolar stress response are emerging. Here, we demonstrate that ribosomal stress...
  • dataset

    Magnitude and influence of atmospheric phosphorus deposition on the southern ...

    Abstract Background There are various ways for nutrients to enter aquatic ecosystems causing eutrophication. Phosphorus deposition through precipitation can be one pathway,...
  • dataset

    Sitagliptin does not reduce the risk of cardiovascular death or hospitalizati...

    Abstract Background To examine the effects of the DPP-4i sitagliptin on CV outcomes during and after incident MI in the Trial Evaluating Cardiovascular Outcomes with Sitagliptin...
  • dataset

    Tranexamic acid and rosuvastatin in patients at risk of cardiovascular events...

    Abstract Background Surgical bleeding is associated with postoperative cardiovascular complications. The efficacy and safety of tranexamic acid (TXA) in noncardiac surgery are...
  • dataset

    Additional file 2: of Effect of delayed misoprostol dosing interval for induc...

    Figure S1. Individual between-dose intervals for routine (blue) and delayed (red) administration groups. (JPG 2256 kb)
  • dataset

    dedup_wf_001--cff1dac5252e02e12bfd323f52db5ec6

    Additional file 1: Figure S1. Dynamics of inflammatory mechanims across DCI beyond 48 hours. A cluster including VEGF, FGF2, IL12p70, IL17A and IFNg, and separate small cluster...
  • dataset

    Using focused pharmacovigilance for ensuring patient safety against antileish...

    Abstract Background Adverse effects of antileishmanial drugs can affect patients’ quality of life and adherence to therapy for visceral leishmaniasis (VL) and post-kala-azar...
  • dataset

    The First Framework Solid Composed of Vanadosilicate Clusters

    In this Communication, we report the first example of a network structure composed of vanadosilicate clusters. We utilized hydrothermal conditions to synthesize a...
  • dataset

    Additional file 18 of Some data quality issues at ClinicalTrials.gov

    Processing of PI names to identify ambiguities—step 2. (XLSX 1406 kb)
  • dataset

    Therapeutic potential of mesenchymal stem cells and their exosomes in severe ...

    Abstract The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19) and the ensuing...
  • dataset

    Visualization 2: Focusing light with orbital angular momentum by circular arr...

    Electric field distribution of the vortex beam measured in time-domain. Originally published in Optics Express on 12 June 2017 (oe-25-12-13728)
  • dataset

    Integrating phenotype ontologies with PhenomeNET

    Abstract Background Integration and analysis of phenotype data from humans and model organisms is a key challenge in building our understanding of normal biology and...
  • dataset

    Additional file 2: of Case report: severe asymptomatic hyponatremia in Prader...

    Time-line summarizing the clinical course of the child described in this case report. (PPTX 76Â kb)
  • dataset

    Biofeedback in the prophylactic treatment of medication overuse headache: a p...

    Abstract Background Medication overuse headache (MOH) is a major clinical concern and a common health risk. Recent literature stressed the need to manage chronic headache by...
  • dataset

    dedup_wf_001--e1fcdbdd4512c7c138ebf389ab1b963e

    This paper summarizes the results of a study focused on the hydrogeological characterization and recognition of groundwater resources in continental southern Italy, developed...
  • dataset

    Additional file 3: of Alternative DNA secondary structure formation affects R...

    A list of 5959 pausing sites located outside of RefSeq gene bodies. (DAT 234 kb)
  • dataset

    Assessment of overall treatment effect in the presence of inconsistent region...

    The use of multi-regional clinical trials (MRCTs) in clinical developments increased to accelerate patients’ access to new drugs globally. MRCTs inherently assume that the...
  • dataset

    MOESM7 of How are nature based solutions contributing to priority societal ch...

    Additional file 7. Assessment of search string for test list.
  • dataset

    A population-based analysis of the risk of drug interaction between clarithro...

    Abstract Background Clarithromycin, known as a potent inhibitor of the cytochrome P450 isoenzyme CYP3A, may increase the plasma concentration of statins metabolized by this...