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The diagnostic accuracy of the hand-held Raman spectrometer for the identific...
Abstract Background There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to... -
Integrative assessment of brain and bone invasion in meningioma patients
Abstract Background Various prognostic factors have been suggested in meningioma patients including WHO grading, brain invasion and bone involvement, for instance. Brain... -
Patients' preferences for involvement in the decision-making process for trea...
Abstract Background To assess factors associated with the preferred role of the attending ophthalmologist in the decision-making processes before treating diabetic retinopathy... -
Spirometric changes during exacerbations of COPD: a post hoc analysis of the ...
Abstract Background Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with loss of lung function and poor outcomes for patients. However, there are... -
Improving cooperation between general practitioners and dermatologists via te...
Abstract Background Internationally, teledermatology has proven to be a viable alternative to conventional physical referrals. Travel cost and referral times are reduced while... -
Structured reporting of x-rays for atraumatic shoulder pain: advantages over ...
Abstract Background To analyse structured and free text reports of shoulder X-ray examinations evaluating the quality of reports and potential contributions to clinical... -
The impairment of small nerve fibers in severe sepsis and septic shock
Abstract Background A decrease of small nerve fibers in skin biopsies during the course of critical illness has been demonstrated recently. However, the diagnostic use of skin... -
Promotion of physical activity-related health competence in physical educatio...
Abstract Background One central goal of physical education in many countries is to empower students to be physically active throughout their lifespan. Physical activity-related... -
Homozygous TBC1 domain-containing kinase (TBCK) mutation causes a novel lysos...
Abstract Homozygous mutation of TBC1 domain-containing kinase (TBCK) is the cause of a very recently defined severe childhood disorder, which is characterized by severe... -
Patient safety, cost-effectiveness, and quality of life: reduction of deliriu...
Abstract Background Postoperative delirium is a common disorder in older adults that is associated with higher morbidity and mortality, prolonged cognitive impairment,... -
Suspicion of respiratory tract infection with multidrug-resistant Enterobacte...
Abstract Background Multidrug-resistant (MDR) infections are a serious concern for children admitted to the Paediatric Intensive Care Unit (PICU). Tracheal colonization with MDR... -
Anticipation of difficult tasks: neural correlates of negative emotions and e...
Abstract Background Difficult cognitive tasks are often associated with negative feelings. This can be already the case for the mere anticipation of having to do a difficult... -
Local measles vaccination gaps in Germany and the role of vaccination providers
Abstract Background Measles elimination in Europe is an urgent public health goal, yet despite the efforts of its member states, vaccination gaps and outbreaks occur. This study... -
Position statement on access to care in rare liver diseases: advancements of ...
Abstract The European Reference Network for rare liver diseases (ERN RARE-LIVER) is a Europe-wide network of paediatric and adult hepatologists from expert centres in close... -
Tigecycline in critically ill patients on continuous renal replacement therap...
Abstract Background Tigecycline is a vital antibiotic treatment option for infections caused by multiresistant bacteria in the intensive care unit (ICU). Acute kidney injury... -
Schistosoma haematobium infection morbidity, praziquantel effectiveness and r...
Abstract Background Sub-Saharan Africa carries most of the global burden of schistosomiasis. To optimize disease control and reduce morbidity, precise data are needed for... -
Diazepam and ethanol differently modulate neuronal activity in organotypic co...
Abstract Background The pharmacodynamic results of diazepam and ethanol administration are similar, in that each can mediate amnestic and sedative-hypnotic effects. Although... -
Risk assessment of manual handling operations at work with the key indicator ...
Abstract Background Manual handling operations (MHO) are known to be risk factors for work-related upper limb disorders (WRULDs), e.g. symptoms and conditions such as carpal... -
Individualised stepwise adaptive treatment for 3–6-year-old preschool childre...
Abstract Background Attention-deficit/hyperactivity disorder (ADHD) is a psychosocially impairing and cost-intensive mental disorder, with first symptoms occurring in early... -
Individualised short-term therapy for adolescents impaired by attention-defic...
Abstract Background Despite the high persistence rate of attention-deficit/hyperactivity disorder (ADHD) throughout the lifespan, there is a considerable gap in knowledge...