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r37980778c78--a53b45f678a186371e2191f6aa1b0375
Due to its function in the rate limiting initial step of the renin-angiotensin system, renin is a particularly promising target for drugs designed to control hypertension, a... -
dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7
A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary... -
Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (...
A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and... -
In vitro and In vivo Optical Imaging Using Water-Dispersible, Noncytotoxic, L...
A facile method for synthesis of monodisperse, biocompatible, silica coated CdSe/CdS/ZnS quantum rods (QRs) and their use as probes for in vitro and in vivo optical bioimaging... -
Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydr...
A series of 3-descladinosyl-2,3-anhydro-6-O-methylerythromycin A 11,12-carbamate analogues have been synthesized and evaluated for antibacterial activity. These compounds were... -
Integrated Comparison of Drug-Related and Drug-Induced Ultra Performance Liqu...
The biochemical variations induced in human primary hepatocyte cultures by reference activators of xenoreceptor CAR (NR1I3) and PXR (NR1I2), i.e., rifampicin, phenobarbital, and... -
r37980778c78--171b2989a7b99d872f8aab415bba7cb6
A new and promising group of antibacterial agents, collectively known as the oxazolidinones and exemplified by linezolid (PNU-100766, marketed as Zyvox), have recently emerged... -
Additional file 1: Tables S1-S3. of Endocrine and exocrine pancreatic insuffi...
Comparision on the disease severity, complication and pancreatic necrosis between NGT, IGT and DM groups. The APACHE II score and Balthazar score in group DM was significant... -
Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
Low-Band-Gap, σ-Conjugated Polymers: Poly(diarylstannanes)
Low-Band-Gap, σ-Conjugated Polymers: Poly(diarylstannanes) -
Solvation and Dynamic Behavior of Cyclodextrins in Dimethyl Sulfoxide Solution
High-frequency dielectric relaxation behavior up to 20 GHz was investigated for plain (α, β, γ) and (62 and 100%) methylated cyclodextrins, CDs, in dimethyl sulfoxide, DMSO,... -
Additional file 1 of Anti-malarial activity of traditional Kampo medicine Cop...
Additional file 1: Table S1. List of crud drug extracts in Kampo library. Table S2. List of compounds in Kampo library. Table S3. In vitro anti-malarial activities against P.... -
dedup_wf_001--eff8f5bc9de3d863386184c6fe5b1db4
Additional file 1: Figure S1. The secondary lymphoid tissues other than GALT appear normal in β7-F185A KI and β7-KO mice. Representative histological sections of the peripheral... -
Phytochemical analysis, antimicrobial, antioxidant and urease inhibitory pote...
In this paper we report the antimicrobial, antiradical and urease inhibitory potential along with photochemical investigation of the crude extracts of Cyphostemma digitatum Lam.... -
dedup_wf_001--6b045eabe5af17717c92a951ca5861f2
Additional file 1: Table S1. National Drug Codes (NDC) for Varenicline. This supplementary table includes the full list of national drug codes for all varenicline formulations.... -
Preparation and unequivocal identification of the regioisomers of nitrocatech...
ABSTRACTThe four positional isomers of nitrocatechol monobenzyl ether were prepared as intermediates to nitrobenzodioxanes directly from 2-benzyloxyphenol or, through two-four... -
Sensitive and Convenient Yeast Reporter Assay for High-Throughput Analysis by...
The yeast reporter assay has been widely used in various applications such as detection of endocrine disruptors and analysis of protein−protein interactions by the yeast... -
Kinetics and mechanism of interaction of Pt(II) complex with bio-active ligan...
Kinetics of interaction between Pt(pic)(H2O)22, 2 (where pic = 2-aminomethylpyridine) with the selected ligands DL-methionine (DL-meth) and DL-penicillamine (DL-pen) have been... -
Evaluation of a Pseudoephedrine Linker for Asymmetric Alkylations on Solid Phase
Immobilized pseudoephedrine amides have been conveniently prepared by attachment of pseudoephedrine to Merrifield resin and acylation on nitrogen. Deprotonation and alkylation... -
Identifying research gaps in substance use disorder: A systematic methodology...
Background: This paper presents a new methodology for identifying and prioritizing research gaps, contributing to the nascent literature on systematic ways to identify research...
