Additional file 1 of Anti-malarial activity of traditional Kampo medicine Coptis rhizome extract and its major active compounds

Additional file 1: Table S1. List of crud drug extracts in Kampo library. Table S2. List of compounds in Kampo library. Table S3. In vitro anti-malarial activities against P. falciparum CQ/mefloquine (MQ)-sensitive (3D7) strains and the cytotoxicities using adult mouse brain cell (AMB) of crude drug extracts. Table S4. Formulation of herbal extracts percentage by weight in Orengedokuto (Toyama verses Tsumura composition of Kampo formula Orengedokuto). Table S5. The average percentage parasitaemia and suppression profile of Orengedokuto and Coptis rhizome. Table S6. Detection of Coptis rhizome and its bioactive compounds in mice fed with Orengedokuto and Coptis rhizome. Figure S1. LCMS chromatogram of Coptis rhizome and Orengedokuto treated mice plasma. Table S7. The average percentage parasitaemia and suppression profile of coptisine chloride.

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PID https://www.doi.org/10.6084/m9.figshare.12450440.v1
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Author Awet Alem Teklemichael
Author Mizukami, Shusaku
Author Toume, Kazufumi
Author Mosaddeque, Farhana
Author Kamel, Mohamed Gomaa
Author Kaneko, Osamu
Author Komatsu, Katsuko
Author Juntra Karbwang
Author Nguyen Tien Huy
Author Hirayama, Kenji, 0000-0001-9467-1777
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Publication Date 2020-06-08
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keyword FOS: Chemical sciences
keyword FOS: Biological sciences
keyword FOS: Earth and related environmental sciences
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Source https://science-innovation-policy.openaire.eu/search/publication?articleId=dedup_wf_001::9911c8338a5d901dd9a95de74469c8cb
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Last Updated 27 December 2020, 00:10 (CET)
Created 27 December 2020, 00:10 (CET)