Patterns of relative INSTI susceptibility for 1,536 viruses in HIVDB with 209 distinct INSTI-Resistance patterns*.

(a,b,c) Multivariable Cox regression analysis assessing factors associated with tenofovir discontinuation regardless of the reason, because of toxicity and with selective...

Composition of the NRTI back-bone of the regimen started after the discontinuation of tenofovir (rows), according to the initial third drug (columns)–All tenofovir...

Baseline participant characteristics.

In vitro susceptibilities associated with the 14 INSTI drug resistance mutation patterns.

Patterns of predicted relative NRTI susceptibility profiles for 35,377 viruses in HIVDB with 4,749 Distinct NRTI-Resistance patterns*.

Data set (XLS)

Treatment-emergent substitutions: Participants meeting drug-resistance testing criteria.

Proportion of responders with HIV-1 RNA <40 copies/mL (Week 24 snapshot) (mITT).

Safety summary through Week 24.

GSK3532795 (formerly known as BMS-955176) is a second-generation maturation inhibitor targeting a specific Gag cleavage site between capsid p24 and spacer peptide 1 of HIV-1....

In vitro susceptibilities associated with the 13 NRTI drug resistance mutation (DRM) patterns.

Factors associated with rates of serum creatinine monitoring after ART initiation.

In vitro susceptibilities associated with the 9 NNRTI drug resistance mutation patterns.

The pharmacokinetic properties of tenofovir (TFV) and other charged nucleoside analogues are dramatically improved upon conjugation to a lipid prodrug. We previously prepared...

Materials available for review by the expert panel.

Patterns of predicted relative PI susceptibility profiles for 19,379 viruses in HIVDB with 5,634 distinct PI-Resistance patterns*.

BackgroundIn resource-limited settings, routine monitoring of renal function during antiretroviral therapy (ART) has not been recommended. However, concerns for tenofovir...

Comparison of the HIVDB version 7.0, expert panel median, and eventual HIVDB version 8.1 levels for the 20 DRM pattern / ARV combinations with a difference between HIVDB version...

List of antiretroviral (ARV) drugs and their abbreviations by ARV class.