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Perylene Synthesis by the Parallel Cycloaromatization of Adjacent Enediynes
As part of an investigation into new synthetic routes to poly(peri-naphthalene), the synthesis and cycloaromatization of tetraethynylbiphenyls is described. The... -
Stereochemical Features of the Physical and Chemical Interactions of Singlet ...
Oxazolidinone-substituted enecarbamates represent a mechanistically rich system for the study of stereoelectronic, steric, and conformational effects on stereoselectivity and... -
Regioselective Carboindation of Simple Alkenes with Indium Tribromide and Ket...
The regioselective carboindation of simple alkenes with indium tribromide and ketene silyl acetals was accomplished. Various alkenes such as ethylene, 1-alkenes, and cyclic... -
Unusual π-Donating Effects of π-Accepting Substituents on the Stabilities of ...
The π-donating effects of π-accepting X-substituents in substituted benzylic cations, X−C6H5−CHR+ where R = CF3, H and OCH3, and X = p-NH2, p-OCH3, p-CH3, H, p-F, p-Cl, p-CHO,... -
Confined Polar Mixtures within Cylindrical Nanocavities
Using molecular dynamics experiments, we have extended our previous analysis of equimolar mixtures of water and acetonitrile confined between silica walls [J. Phys. Chem. B... -
Effect of a 17α-(3-Hydroxypropyl)-17β-acetyl Substituent Pattern on the Gluco...
Replacing the 17α-acetoxy substituent in an antiprogestational 17β-acetyl-11β-arylestra-4,9-dien-3-one by 3-hydroxypropyl significantly diminished glucocorticoid receptor... -
Aryl Bridged 1-Hydroxypyridin-2-one: Effect of the Bridge on the Eu(III) Sens...
The efficiency of Eu3+ luminescence by energy transfer from an antenna ligand can be strongly dependent on the metal ion coordination geometry. The geometric component of the... -
On the Stereospecific Conversion of Proximally-Oxygenated Trisubstituted Viny...
Allylically oxygenated vinyl α-triphenylstannanes such as 22 can be readily converted into vinyl iodides and thereafter stereodefined trisubstituted alkenes with retention of... -
Thermodynamic Behavior of Poly(3-alkyl Thiophene) Blends: Equilibrium Cocrys...
The equilibrium cocrystal formation of poly(3-alkyl thiophene) (P3AT) blends has been studied by isothermal cocrystallization in a differential scanning calorimeter (DSC-7). The... -
Release of Nitrosating Species in the Course of Reduction of Benzo-1,2,3,4-te...
The reduction of benzo-1,2,3,4-tetrazine 1,3-dioxides (BTDOs) 1 with Na2S2O4 or SnCl2 is suggested to proceed via intermediate N-nitrosobenzotriazoles 3 to afford benzotriazoles... -
Sagittamides A and B. Polyacetoxy Long-Chain Acyl Amino Acids from a Didemnid...
An unidentified tunicate from Pohnpei, Micronesia, yielded sagittamides A and Bcompounds comprising a long-chain C26 dicarboxylic acid that acylates terminal l-valine and... -
Asymmetric Total Synthesis of the Proposed Structure of the Medicinal Alkaloi...
A highly step-economic asymmetric synthesis of the tetracyclic structure assigned to the medicinal alkaloid jamtine has been accomplished using a chiral lithium amide base... -
Design and Synthesis of Potent Cystine-Free Cyclic Hexapeptide Agonists at th...
Cyclic hexapeptides, incorporating a dipeptide unit in place of the disulfide bond found in urotensin, were prepared and screened at the human urotensin receptor. The bridging... -
Infrared and Computational Studies of the Adsorption of Methanol and Ethanol ...
The adsorption of methanol and ethanol on room-temperature single-walled carbon nanotubes (SWCNTs) has been investigated using Fourier transform infrared (FTIR) spectroscopy and... -
Precipiton Reagents: Precipiton Phosphines for Solution-Phase Reductions
Several Precipiton phosphines were prepared and employed in the Staudinger reaction and in the reduction of secondary ozonides. Both amines and aldehdyes were obtained in good... -
Total Synthesis of (±)-Hedychenone: Trimethyldecalin Terpene Systems via Ste...
The total synthesis of hedychenone 1 is described. The cycloaddition of the hindered diene 2 and the allenecarboxylate 3 has been shown conclusively to proceed via the [2+2]... -
Commercialization and Late-Stage Development of a Semisynthetic Antifungal AP...
Many years ago anidulafungin 1 was identified as a potentially useful medicine for the treatment of fungal infections. Its chemical and physical properties as a relatively high... -
Pore Shape Affects Spontaneous Charge Redistribution in Small Pores
A complete understanding of charge redistribution (spontaneous movement of charge once the system has been placed on open-circuit) in porous materials is desirable because... -
Ab Initio Study on the Oxidation of NCN by OH: Prediction of the Individual a...
The mechanism for the reaction of NCN with OH has been investigated by ab initio molecular orbital and transition-state theory calculations. The potential energy surface (PES)... -
A Theoretical Study of the Chorismate Synthase Reaction
: Density functional calculations (B3LYP/6-31+G(d,p)) were carried out to investigate the mechanism of the anti-1,4-elimination of phosphate from...
