(CSV)

Oligonucleotide sequences for real-time RT-PCR.

We present a selection design that couples S-adenosylmethionine–dependent methylation to growth. We demonstrate its use in improving the enzyme activities of not only N-type and...

Introduction: Due to its close connection with the renal system, urine is considered a valuable source of information in kidney disease research. Peptidomics methods focus on...

(XLSX)

Predicting the fraction unbound in plasma provides a good understanding of the pharmacokinetic properties of a drug to assist candidate selection in the early stages of drug...

Anticipated advantages and drawbacks of Actual Home Cage Analyzer™ over existing technologies in rats

The semantic concepts with the highest weights for T2D are focused on glucose homeostasis or tolerance as well as insulin resistance, sensitivity, levels, secretion, and the...

Drug-induced cardiovascular complications are the most common adverse drug events and account for the withdrawal or severe restrictions on the use of multitudinous postmarketed...

Part 2 of Databases S1 (transcriptomic data) BCG_BDM41906.fastq

Clinical trials targeting bromodomains and registered on ClinicalTrials.gov (National Library of Medicine and National Institutes of Health, United States), as of 1 January 2015.

a Liu et al., 2011 [19]. b Ji et al., 2007 [20]. c Wei et al., 2010 [21]. d Noteborn et al., 2013 [22]. *Positions correspond to: IBDV (JQ684022), IBV (KJ425500), AEV...

Fungi isolated from marine invertebrates are of considerable importance as new promising sources of unique secondary metabolites with significant biomedical potential. However,...

Query results for the top five sparse pharmacophore models.

Data are mean (95% CI).

NA = Not analysed a) Not possible to estimate as the number of studies varies between years. To be evaluated after 2–3 years. b) Not possible to estimate as the number of...

Note: Sample announcements were manually matched with unique clinical trial identifiers provided by ClinicalTrials.gov, a public database.

Notes: All data represent 2012 calendar year financials. Pharmaceutical segment revenues (“Pharma”) represent the amount and proportion of total revenues from branded (i.e....

The number of compounds found to demonstrate inhibition at 10μM overall and with respect to the two different methods of ranking compounds.

Nicotinic acetylcholine receptors (nAChRs) modulate synaptic activity in the central nervous system. The α7 subtype, in particular, has attracted considerable interest in drug...