Distribution of the top three most frequently searched SMQs for the top three therapeutic classes represented by the second level of the ATC classification systema,b.

Demographic and content variables collected from the review documents.

Stability data under different storage conditions (Table A). The individual animal pharmacokinetic data of ALP (Table B), OXP (Table C), and LES (Table D). (ZIP)

Extraction recovery and matrix effects data of ALP, OXP, LES and IS in rat plasma (n = 5).

Inter and inter-day precision and accuracy data of ALP, OXP and LES in rat plasma.

Optimized compound specific parameters for ALP, OXP, LES and IS.

Confirmation approaches used for top five most frequently searched SMQs.

The non-compartmental pharmacokinetic parameters for ALP, OXP and LES in rat plasma after oral administration of mg/kg of ALP and 15 mg/kg of LES.