Background Hyperemesis gravidarum (HG), or intractable vomiting during pregnancy, is the single most frequent cause of hospital admission in early pregnancy. HG has a major...

Background The howRu and howRwe are new short questionnaires which are meant to measure health-related quality of life and patient experience. However, validation at the...

Background Despite the detrimental effects of physical inactivity for older adults, especially aged residents of residential care settings may spend much time in inactive...

Background Polypharmacy and inappropriate drug use is associated with negative health outcomes among older people. Various interventions for improving drug...

Background Duchenne Muscular Dystrophy (DMD) is a rapidly progressive, lethal neuromuscular disorder, present from birth, which occurs almost exclusively in males. We have...

Objective: An often reported side-effect of a cochlear implant (CI) is suppression of tinnitus. However, induction of tinnitus is also a known complication of CI surgery. To...

Background The affliction of allergic rhinitis (AR) has been trivialised in the past. Recent initiatives by the European Academy of Allergy & Clinical Immunology and by the...

Purpose: The current study aimed to evaluate the psychometric properties of the Dutch version of the Multiple Sclerosis Work Difficulties Questionnaire-23 (MSWDQ-23). Methods:...

Purpose: To examine the associations between residents’ personality traits, type of specialty, and symptoms of burnout. Method: A cross-sectional online survey among Dutch...

Background: The population of breast cancer survivors is increasing as a positive consequence of early detection and enhanced treatment. The disease and treatment associated...

Background Inhaled drug delivery is the cornerstone treatment for asthma and chronic obstructive pulmonary disease (COPD). However, use of inhaler devices can be challenging,...

Background: Thus far there have been no specific patient-reported outcome instrument in Finnish for health-related quality of life (HRQoL) assessment after major lower extremity...

PURPOSE/OBJECTIVE: Chemo-radiotherapy is an established primary curative treatment for anal cancer, but clinically equal rationale for different target doses exists. If joint...

Objective: A mixed treatment comparison (MTC) was performed to investigate the relative efficacy and safety of licensed pharmaceuticals for moderate-to-severe restless legs...

Background It has often been hypothesized that the frequency of follow-up visits for patients with early-stage endometrial cancer could be decreased. However, studies evaluating...

Greening schoolyards is an initiative to reconnect children with nature and afford meaningful experiences that foster children's well-being. To strengthen the empirical basis...

Background Pre-operative chemoradiotherapy (CRT) for MRI-defined, locally advanced rectal cancer is primarily intended to reduce local recurrence rates by downstaging tumours,...

Background Pressures on informal caregivers are likely to increase due to increasing life expectancy and health care costs, which stresses the importance of prevention of...

Abstract Background Duchenne Muscular Dystrophy (DMD) is a rapidly progressive, lethal neuromuscular disorder, present from birth, which occurs almost exclusively in males. We...

Abstract Background Despite the detrimental effects of physical inactivity for older adults, especially aged residents of residential care settings may spend much time in...