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Computation of adherence to medication and visualization of medication histor...
Adherence to medications is an important indicator of the quality of medication management and impacts on health outcomes and cost-effectiveness of healthcare delivery.... -
Effect of tramadol as an adjuvant to local anesthetics for brachial plexus bl...
Background Tramadol, a 4-phenyl-piperidine analog of codeine, has a unique action in that it has a central opioidergic, noradrenergic, serotonergic analgesic, and peripheral... -
Utilization of smoking cessation medication benefits among medicaid fee-for-s...
Objective To assess state coverage and utilization of Medicaid smoking cessation medication benefits among fee-for-service enrollees who smoked cigarettes. Methods We... -
Inconsistencies among European Union pharmaceutical regulator safety communic...
International audience; BACKGROUND:The European Medicines Agency (EMA) and national regulators share the responsibility to communicate to healthcare providers postmarketing... -
Clinical features of pulmonary embolism in patients with lung cancer: A meta-...
BACKGROUND: Pulmonary embolism (PE) is correlated with increased mortality among patients with lung cancer (LC). The characteristics of patients with LC presenting with PE have... -
BioPETsurv: Methodology and open source software to evaluate biomarkers for p...
Biomarkers can be used to enrich a clinical trial for patients at higher risk for an outcome, a strategy termed "prognostic enrichment." Methodology is needed to evaluate... -
Open source machine-learning algorithms for the prediction of optimal cancer ...
Precision medicine is a rapidly growing area of modern medical science and open source machine-learning codes promise to be a critical component for the successful development... -
Implementation of intermittent theta burst stimulation compared to convention...
Background Repetitive transcranial magnetic stimulation (rTMS) is an evidence-based treatment for depression that is increasingly implemented in healthcare systems across the... -
Trends in mental health clinical research: Characterizing the ClinicalTrials....
While the epidemiologic burden of mental health disorders in the United States has been well described over the past decade, we know relatively little about trends in how these... -
Does dose-dense neoadjuvant chemotherapy have clinically significant prognost...
Purpose Neoadjuvant chemotherapy (NCT) is typically the initial treatment for non-early breast cancer patients. We thereby conducted a meta-analysis to explore whether... -
Industrial perceptions of medicines regulatory harmonization in the East Afri...
Background Medicines regulatory harmonization has been recommended as one way to improve access to quality-assured medicines in low- and middle-income countries. The rationale... -
Modeling timelines for translational science in cancer; the impact of technol...
This work examines translational science in cancer based on theories of innovation that posit a relationship between the maturation of technologies and their capacity to... -
Intermittent epidural bolus versus continuous epidural infusions for labor an...
There are inconsistent results regarding the efficacy and safety of intermittent epidural bolus (IPB) versus continuous epidural infusions (CPI) for labor analgesia. This study... -
Researchers’ attitudes to the 3Rs—An upturned hierarchy?
Animal use in biomedical research is generally justified by its potential benefits to the health of humans, or other animals, or the environment. However, ethical acceptability...
