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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
dedup_wf_001--48e514b0289b59e84c3e4ba25ae2ed55
We explored the impact a new quantitative biology course for biology majors had on their ability and confidence to utilize hypothesis testing. Students currently in the... -
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTOR...
Macroautophagy/autophagy is an evolutionarily conserved process that involves the selective degradation of cytoplasmic components within lysosomes in response to starvation.... -
SUMO conjugation regulates immune signalling
Post-translational modifications (PTMs) are critical drivers and attenuators for proteins that regulate immune signalling cascades in host defence. In this review, we explore... -
RETRACTED ARTICLE: Development of a porous bifunctional metal-organic framewo...
This work presents the synthesis and properties study of a new dual-functional metal-organic framework (MOF) with the chemical formula of [Cu7(nbpt)4(H2O)2(OH)4]·(DMF)5(H2O) (1,... -
Impact of differential and time-dependent autophagy activation on therapeutic...
Activation of macroautophagy/autophagy, a key mechanism involved in the degradation and removal of aggregated proteins, can successfully reverse Huntington disease phenotypes in... -
dedup_wf_001--76d6c0849b62c1fb0e912d7290bfa4ad
Latinos are heavily affected with childhood asthma. Little is known about epigenetic mechanisms of asthma in Latino youth. We conducted a meta-analysis of two epigenome-wide... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
dedup_wf_001--c3b5a24017e46c1b08c553f0bd149f9b
An extractant forced-circulation three-phase extraction (EC-TPE) device based on extraction-stripping coupling was developed for the preconcentration of Cd2+ in environmental... -
Ceric ammonium nitrate/acetic anhydride: A tunable system for the O-acetylati...
Esterification of a wide range of partially protected carbohydrate derivatives was achieved using acetic anhydride and a catalytic amount of ceric ammonium nitrate (CAN).... -
Impact of select PPE design elements and repeated laundering in firefighter p...
As the Fire Service becomes more aware of the potential health effects from occupational exposure to hazardous contaminants, personal protective equipment (PPE) manufacturers,... -
Effect of recombinant human granulocyte colony-stimulating factor on lymphocy...
Effect of recombinant human granulocyte colony-stimulating factor on lymphocyte subsets in patients with COVID-19 -
Methylation Status of VDR Gene and its Association with Vitamin D Status and ...
Deficiency in circulatory vitamin D level and vitamin D receptor DNA methylation could be associated with weakened innate immune response and increased susceptibility to... -
Molecular mechanism of microRNA-21 promoting Schwann cell proliferation and a...
At present, the functional recovery after nerve injury is not satisfactory in clinical practice. The aim of this study was to explore the molecular mechanism of miR-21 promoting... -
Comparison between insulin degludec/liraglutide treatment and insulin glargin...
ABSTRACTAim: To evaluate the efficacy and adverse effects of IDegLira and IGlarLixi treatment and to perform a comparison between two strategies.Methods: The registration number... -
Casein kinases as potential therapeutic targets
Introduction: The conventional term ‘casein kinase’ (CK) denotes three classes of kinases – CK1, CK2 and Golgi-CK (G-CK)/Fam20C (family with sequence similarity 20, member C) –... -
Fractional Exhaled Nitric Oxide as an Inflammatory Biomarker in Chronic Obstr...
We studied whether fractional exhaled nitric oxide (F ENO) can differentiate chronic obstructive pulmonary disease (COPD) with concurrent diagnosis of asthma from COPD-only as... -
miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in huma...
Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated... -
RNA secondary structure at the transcription start site influences EBOV trans...
Ebola virus (EBOV) RNA has the potential to form hairpin structures at the transcription start sequence (TSS) and reinitiation sites of internal genes, both on the genomic and... -
RETRACTED ARTICLE: Structure revision of aspergicin by the crystal structure ...
AbstractThe structure of aspergicin (1), an antibacterial alkaloid produced by co-culture of two marine-derived mangrove epiphytic fungi, were revised by the co-occurring isomer...
