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dedup_wf_001--e8e4f9dc39f84974c9d1edc1cd83afad
Background DNA methylation at cytosine nucleotides constitutes epigenetic gene regulation impacting cellular development and a wide range of diseases. Cytosine bases of the DNA... -
Maternal blood contamination of collected cord blood can be identified using ...
Background: Cord blood is a commonly used tissue in environmental, genetic, and epigenetic population studies due to its ready availability and potential to inform on a... -
MSP-HTPrimer: a high-throughput primer design tool to improve assay design fo...
Background Bisulfite (BS) conversion-based and methylation-sensitive restriction enzyme (MSRE)-based PCR methods have been the most commonly used techniques for locus-specific... -
A novel joint analysis framework improves identification of differentially ex...
Motivation Detecting differentially expressed (DE) genes between disease and normal control group is one of the most common analyses in genome-wide transcriptomic data. Since... -
A multiplexed gas exchange system for increased throughput of photosynthetic ...
Background Existing methods for directly measuring photosynthetic capacity (Amax) have low throughput, which creates a key bottleneck for pre-breeding and ecological research.... -
Soft document clustering using a novel graph covering approach
Background In text mining, document clustering describes the efforts to assign unstructured documents to clusters, which in turn usually refer to topics. Clustering is widely... -
A robust internal control for high-precision DNA methylation analyses by drop...
Background Droplet digital PCR (ddPCR) allows absolute quantification of nucleic acids and has potential for improved non-invasive detection of DNA methylation.... -
Medical subject heading (MeSH) annotations illuminate maize genetics and evol...
Background High-density marker panels and/or whole-genome sequencing, coupled with advanced phenotyping pipelines and sophisticated statistical methods, have dramatically... -
HAM-TBS: high-accuracy methylation measurements via targeted bisulfite sequen...
Background The ability to accurately and efficiently measure DNA methylation is critical to advance the understanding of this epigenetic mechanism and its contribution to common... -
Semantics-based plausible reasoning to extend the knowledge coverage of medic...
Background Capturing complete medical knowledge is challenging-often due to incomplete patient Electronic Health Records (EHR), but also because of valuable, tacit medical...
