MMR gene mutation distribution in endometrial cancer patients.

BackgroundLynch syndrome is a hereditary cancer syndrome caused by constitutional pathogenic variants in the DNA mismatch repair (MMR) system, leading to increased risk of...

SSA-Sub Saharan and Southern Africa, SEA-South and South-East Asia. 1These cost-effectiveness results are for the whole region in SSA, and for populations at risk of malaria...

Table S2. All six family members gene test result. All six family members gene test results displayed in order of gene. (XLSX 770 kb)

Table S1. 101 gene panel. The gene list of targeted capture panel used in the case. (XLSX 11Â kb)

AbstractBackgroundHereditary cancer screening (HCS) for germline variants in the 3’ exons of PMS2, a mismatch repair gene implicated in Lynch syndrome, is technically...

Background Lynch syndrome (LS) is caused by mutations in DNA mismatch repair (MMR) genes, which accounts for 3–5% of colorectal cancer. The risks of several types of cancer are...

Key design criteria for economic evaluation.