Abstract Background Little is known about determinants of quality of life (QoL) in autosomal dominant polycystic kidney disease (ADPKD). Recent studies suggest that QoL in ADPKD...

Introduction: The kidney is a major target for toxicity elicited by pharmaceuticals and environmental pollutants. Standard testing which often does not investigate underlying...

This data file includes empirical scoring data for the manuscript submitted for full review to the eLife journal. Each spreadsheet contains the scoring data for individual...

Background Lipotoxicity plays an important role in the pathogenesis of kidney injury. Our previous study demonstrated that activation of local renin-angiotensin system (RAS) was...

Background Plant medicinal extracts may be claimed to prevent or cure chemical intoxications. Few of these are tested for their mechanisms of actions in vivo and for their...

Figure A3. Combination treatment with chymostatin and aliskiren markedly prevented ER stress and apoptosis in primary cultured tubular cells treated with palmitic acid (0.2 mM)...

Background A number of dysregulated miRNAs have been identified and are proposed to have significant roles in the pathogenesis of type 2 diabetes mellitus or renal pathology....

Raw data for locomotor activity and biochemical parameters of rats treated with Roundup (R), Dig1 (D), Dig1+Roundup (D+R) in comaprison to controls (C). Excel sheet1: front...

R code for submitted Biology Letters paper to be run in conjunction with other data stored in gametophyte ecology prohect

of Complement regulator CD59 prevents peripheral organ injury in rats made seropositive for neuromyelitis optica immunoglobulin G