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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
dedup_wf_001--aad5de0a2207e226aec94d5ef408710b
A previous survey investigated postmenopausal vaginal atrophy in a sample of women across Latin America. To help implement a tailored approach to improve postmenopausal care and... -
Eye Injuries and Related Risk Factors among Workers in Small-scale Industrial...
PURPOSE We aimed to study eye injuries and their risk factors among workers at small-scale industrial enterprises. METHODS Cross-sectional descriptive study. Five hundred... -
dedup_wf_001--112619b9a890dbb702d8f88e294728a0
We systematically reviewed adverse events (AEs) for ocrelizumab for multiple sclerosis (MS). We searched Medline, Embase, Web of Science, and Toxicology Data Network-TOXLINE... -
dedup_wf_001--213f0b34bc1cd5e5b423276cd6b90694
To assess the real-world effectiveness of golimumab in Japanese patients with rheumatoid arthritis who had previously received first-line biologic therapy. A post-hoc analysis... -
Renal complications in COVID-19: a systematic review and meta-analysis
Emerging data suggest that coronavirus disease 2019 (COVID-19) has extrapulmonary manifestations but its renal manifestations are not clearly defined. We aimed to evaluate renal... -
Vehicle safety characteristics in vulnerable driver populations
National data suggest drivers who are younger, older, and have lower socioeconomic status (SES) have heightened crash-related injury rates. Ensuring vulnerable drivers are in... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
dedup_wf_001--5101a4e2d80df72a31b34d26c9459e57
A coke produced using a custom-built sole-heated oven and a coke prepared in a pilot-scale oven from a matched coal, were compared using a range of analytical techniques. The... -
Potential Precursor of Angiotensin-I Converting Enzyme (ACE) Inhibitory Activ...
Peptic hydrolysates were prepared by digesting the cutlassfish muscle protein using pepsin for 1, 3, and 6 h, and their inhibitory activity against angiotensin-I converting... -
dedup_wf_001--658fc3cf8a8d8f5a82fe6ffb7ee075c2
Purpose: This study aimed to define the behavioral determinants influencing the decision of intensivists to consult a poison center (PC) when managing patients with calcium... -
Safety evaluation of immune-based combinations in patients with advanced rena...
Immune-based combinations, including nivolumab plus ipilimumab, pembrolizumab plus axitinib, and (at a lesser extent) avelumab plus axitinib, should be regarded among the new... -
The Design and Analysis for the Icing Wind Tunnel Experiment of a New Deicing...
A new kind of deicing coating is developed to provide aircraft with efficient and durable protection from icing-induced dangers. The icing wind tunnel experiment is... -
Impact of immunogenicity on efficacy and tolerability of tumour necrosis fact...
SB4, SB2, and SB5 are biosimilars of etanercept (ETN), infliximab (INF), and adalimumab (ADA), respectively. This pooled analysis evaluated the immunogenicity of these... -
Cost-effectiveness of ceftolozane/tazobactam plus metronidazole compared with...
Aims: An increase in the prevalence of antimicrobial resistance among gram-negative pathogens has been noted recently.[1] A challenge in empiric treatment of complicated... -
dedup_wf_001--59716430bf39cad654eeab4b69760468
A physiologically based pharmacokinetic (PBPK) model for di-isononyl phthalate (DiNP) was developed by adapting the existing models for di(2-ethylhexyl) phthalate (DEHP) and... -
Immune-mediated inflammatory disease patients' preferences in adverse drug re...
Objectives: Patient-reported outcomes (PROs) are increasingly used in studies and medical practice to obtain information on patients’ perspectives toward their treatment or... -
A novel and effective natural product-based immunodetection tool for TNT-like...
This study aimed to develop a fast and reliable protocol for Trinitrophenol-Tris(hydroxymethyl)aminomethane (TNP-Tris) detection applying a β-lactamase-fusion protein of choice,... -
dedup_wf_001--85e1e77b61e09eda8306fe2d0c80bb68
To assess gout and asymptomatic hyperuricemia in Japan and review treatment conditions. This retrospective cross-sectional study analyzed the prevalence of hyperuricemia and... -
Considerations on COVID-19 pregnancy: a cases series during outbreak in Berga...
COVID-19 has rapidly spread worldwide, with severe complications affecting particularly elderly and compromised subjects. Less information about COVID-19 in pregnancy has been...