798 items found

Types: other Tags: Genetics Microbiology

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    Correction to: Isolation and genetic characterization of Toxoplasma gondii in...

    An amendment to this paper has been published and can be accessed via the original article.
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    The impact of genomic selection on genetic diversity and genetic gain in thre...

    Abstract Background In France, implementation of genomic evaluations in dairy cattle breeds started in 2009 and this has modified the breeding schemes drastically. In this...
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    Development of a promoter shutoff system in <i>Aspergillus oryzae</i> using a...

    Promoter shutoff is a general method for analyzing essential genes, but in the fungus Aspergillus oryzae, no tightly repressed promoters have been reported. To overcome the...
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    Condition-specific promoter activities in Saccharomyces cerevisiae

    Abstract Background Saccharomyces cerevisiae is widely studied for production of biofuels and biochemicals. To improve production efficiency under industrially relevant...
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    Involvement of ABC-transporters and acyltransferase 1 in intracellular choles...

    Abstract Background Understanding pathogenic mechanisms is imperative for developing novel treatment to the tuberculosis, an important public health burden worldwide. Recent...
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    Molecular characteristics of Staphylococcus aureus isolates from food surveil...

    Abstract Background Staphylococcal food poisoning (SFP) is one of the most common food-borne diseases in the world. Pulsed-field gel electrophoresis (PFGE), multilocus sequence...
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    Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black ...

    Abstract Background Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood...
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    Boron-deficiency-responsive microRNAs and their targets in Citrus sinensis le...

    Abstract Background MicroRNAs play important roles in the adaptive responses of plants to nutrient deficiencies. Most research, however, has focused on nitrogen (N), phosphorus...
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    Managing or restricting movement? Diverging approaches of African and Europea...

    Abstract Though a common EU-African agenda of dealing with migration goes back at least a decade with bilateral, regional and continental approaches, it has gained in visible...
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    Factors associated with the development of septic shock in patients with cand...

    Abstract Background Almost one third of the patients with candidemia develop septic shock. The understanding why some patients do and others do not develop septic shock is very...
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    Patternable particle microarray utilizing controllable particle delivery

    Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and...
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    Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb del...

    Abstract Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant...
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    CRISPR/dCas9-mediated transcriptional improvement of the biosynthetic gene cl...

    Abstract Background The CRISPR/dCas9 system is a powerful tool to activate the transcription of target genes in eukaryotic or prokaryotic cells, but lacks assays in complex...
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    Efficient production of extracellular pullulanase in Bacillus subtilis ATCC60...

    Abstract Background Bacillus subtilis has been widely used as a host for heterologous protein expression in food industry. B. subtilis ATCC6051 is an alternative expression host...
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    Reduction of spherical-aberration impact in microscopy by wavefront coding

    In modern high-NA optical scanning instruments, like scanning microscopes, the refractive-index mismatch between the sample and the immersion medium introduces a significant...
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    Additional file 7: of The prominent alteration in transcriptome and metabolom...

    Table S7. The homologous genes between M. bovis BCG and M. tuberculosis H37Rv. (XLS 1840 kb)
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    Identification of interchangeable cross-species function of elongation factor...

    Abstract Background Tick-borne Babesia bigemina is responsible for acute and potentially lethal hemolytic disease in cattle. The development of genetic manipulation tools...
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    Genetic boundaries delineate the potential human pathogen Salmonella bongori ...

    Abstract Background Salmonella bongori infect mainly cold-blooded hosts, but infections by S. bongori in warm-blooded hosts have been reported. We hypothesized that S. bongori...
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    Pilot study comparing the Childhood Arthritis &amp; Rheumatology Research All...

    Abstract Objectives To assess the feasibility of studying the comparative effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment...
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    The contribution of culturomics to the repertoire of isolated human bacterial...

    Abstract After a decade of research and metagenomic analyses, our knowledge of the human microbiota appears to have reached a plateau despite promising results. In many studies,...