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Functional crosstalk between mTORC1/p70S6K pathway and heterochromatin organi...
Abstract Background Stem cell senescence has been proposed as one of the major drivers of aging, and MSC senescence contributes to aging-related diseases. Activation of mTORC1... -
A mathematical model provides mechanistic links to temporal patterns in Droso...
Abstract Background Circadian clocks are endogenous biochemical oscillators that control daily behavioral rhythms in all living organisms. In fruit fly, the circadian rhythms... -
dedup_wf_001--678de25d4a66913eeaf6f1bd36b33ffe
Additional file 1. Representative standard curve and amplification plot from each let-7 family member RT-qPCR. Standard curve and amplification plot from (A) let-7a, (B) let-7b,... -
Different risk factor patterns for adult asthma, rhinitis and eczema: results...
Abstract Background Atopic diseases including asthma, rhinitis and eczema have increased in the second half of the past century. This has been well studied among children and... -
Figure 4
Nematodes were reared on the indicated bacterium until three days old, then were either left at standard conditions or heat shocked. To quantify offspring, we washed worms off... -
A metagenomic study of the gut microbiome in Behcet’s disease
Abstract Background Behcet’s disease (BD) is a recalcitrant, multisystemic inflammatory disease that can lead to irreversible blindness. Microbial agents have been considered to... -
Waist circumference is associated with major adverse cardiovascular events in...
Abstract Background Although studies have shown that waist circumference (WC) is positively associated with an increased risk of cardiovascular diseases among the normal... -
Sample distribution.
Description of data for mule deer (Odocoileus hemionus) and elk (Cervus canadensis) collected from 20 locations in western North America between 1981 and 2010. -
Additional file 3: of Structure and function of the musculoskeletal oviposito...
Registered SR-μCT images of the section of the metasoma of Venturia canescens that contains the musculoskeletal ovipositor system and animation of the surface rendering of the... -
MOESM3 of Elaboration of bilateral symmetry across Knautia macedonica capitul...
Additional file 3. qPCR relative expression of CYC-like paralogs for dorsal, left lateral, right lateral, and ventral petals of external and internal florets. Standard error... -
Aging
Data documenting post-capture survival in days for wild flies caught across seasonal time and full lifespan of their F1 offspring. -
Additional file 6: Figure S5. of Development of an integrated approach for co...
Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) (A), interleukin (IL)-1α (B), IL-1β (C), IL-5 (D), IL-10 (E), Keratinocyte-derived Chemokine (KC) (F), Macrophage... -
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming gro...
Abstract Background Pirfenidone, an antifibrotic agent used for the treatment of idiopathic pulmonary fibrosis (IPF), functions by inhibiting myofibroblast differentiation,... -
ClC transporter activity modulates histidine catabolism in Lactobacillus reut...
Abstract Background Histamine is a key mediator of the anti-inflammatory activity conferred by the probiotic organism Lactobacillus reuteri ATCC PTA 6475 in animal models of... -
Associations among left ventricular systolic function, tachycardia, and cardi...
Abstract Background In sepsis, tachycardia may indicate low preload, adrenergic stimulation, or both. Adrenergic overstimulation is associated with septic cardiomyopathy. We... -
Visualization of activity-regulated BDNF expression in the living mouse brain...
Abstract Altered levels of brain-derived neurotrophic factor (BDNF) have been reported in neurologically diseased human brains. Therefore, it is important to understand how the... -
The Red Queen in the Repository: metadata quality in an ever-changing environ...
This fileset contains a preprint version of the conference paper (.pdf), presentation slides (as .pptx) and the dataset(s) and validation schema(s) for the IDCC 2019 (Melbourne)... -
Study dataset.
Compliance with NPG checklist items: data dictionary available in project space. In version 2, 7 errors from the previous version at database lock (publication date for PMID...
