Predicted side effects of drugs. The list of 11,152 novel side effects of drugs spanning 39 drugs and 1,598 side effects. (XLSX 179 kb)

Predicted drug indications. The list of 1,816 novel drug indications spanning 47 drugs and 122 diseases. (XLSX 54 kb)

Table S2. Master regulators analysis results. (XLSX 23 kb)

Results of drug repositioning for psoriasis based on CMap and NFFinder for GSE13355. The drug repositioning results by CMap and NFFinder are shown. (XLS 972Â kb)

Table S3. Master regulator candidates subnetwork nodes and edges information. (XLSX 12 kb)

Abstract Background The dominant paradigm in understanding drug action focuses on the intended therapeutic effects and frequent...

Background Malignant pleural mesothelioma (MPM) is an orphan disease that is difficult to treat using traditional chemotherapy, an approach which has been effective in other...

Background Although drug discoveries can provide meaningful insights and significant enhancements in pharmaceutical field, the longevity and cost that it takes can be extensive...

Background Drug repositioning, finding new indications for existing drugs, has gained much recent attention as a potentially efficient and economical strategy for accelerating...