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Model-Based Analysis of Costs and Outcomes of Non-Invasive Prenatal Testing f...
BackgroundNon-invasive prenatal testing (NIPT) for Down’s syndrome (DS) using cell free fetal DNA in maternal blood has the potential to dramatically alter the way prenatal... -
r37980778c78--d9605b88ea6e1e617e7cc7478383d59e
∧Degree of intellectual disability is based on all items of the SRZ.°Unstandardized regression weights.†Unstandardized regression weights adjusted for parental education and... -
General characteristics of the adolescents with Down syndrome (n = 322).
Abbreviation: SD – standard deviation. * Boys with DS compared to girls with DS. ∧Both parents born in the Netherlands. -
Sensitivity and specificity of NIPT for Down’s syndrome: results from eight s...
*Calculated using the Fetal-fraction Optimized Risk of Trisomy Evaluation (FORTE) algorithm. TP = number of true positive results; FN = number of false negative results; TN... -
dedup_wf_001--4044488e051749c768cf17fd4adc132e
Frequency of all influential factors reported by each category of health professional and overall. TDF Theoretical Domains Framework, #IF Influential factor number (see Tables 2... -
Mental Age (MA), IQ, Vineland (VABS) and Child Behavior Checklist (CBCL-Total...
Note: Mean values are presented with standard deviations in parentheses. *N = 20 for T1 VABS Score. 1Vineland Adaptive Behavior Composite Score; 2Child Behavior Checklist... -
Additional file 1: of Intranasal rapamycin ameliorates Alzheimer-like cogniti...
List of antibodies used for WB and IF analysis. For each antibody employed in the study is reported the brand, the catalogue number and the dilution employed in the study. (PPTX... -
dedup_wf_001--c352b6d3c29fbf7d7ad2b99d9e9e3d16
Pilot studies to assess InRapa therapeutic dose. Mice were treated by InRapa daily for 1 week after which brain regions were collected and analyzed. Phosphorylation levels of... -
ダウン症候群患児の脱落乳歯由来幹細胞から分化したドーパミン作動性ニューロンの発達異常に関する研究
Background Down syndrome (DS) is a common developmental disorder resulting from the presence of an additional copy of chromosome 21. Abnormalities in dopamine signaling are... -
Attitude, knowledge and informed choice towards prenatal screening for Down S...
Background Down Syndrome screening test is a bridge between knowledge and uncertainty, safety and risk, unpredictability and desire to know in order to gain control. It may be... -
A scoping review
Background The medical care chain around Down syndrome (DS) is complex, with many multidisciplinary challenges. The current quality of care is unknown. Outcome-oriented quality... -
Intranasal rapamycin ameliorates Alzheimer-like cognitive decline in a mouse ...
Background Down syndrome (DS) individuals, by the age of 40s, are at increased risk to develop Alzheimer-like dementia, with deposition in brain of senile plaques and... -
Key model inputs.
*For both unaffected and DS affected pregnancies. **As for invasive diagnostic tests. ***As for DS screening. DS = Down’s syndrome; NT = nuchal translucency; CVS =...
