The palladium-catalyzed domino cyclization of propargyl bromides having two nucleophilic functional groups is described. Treatment of 1,7-diamino-5-bromohept-3-yne derivatives...

Regiocontrolled synthesis of polysubstituted benzenes from silylated 1,3-dien-5-ynes has been achieved by using diisobutylaluminum hydride (DIBAL-H). Hydroalumination of the...

Moore-Type Cyclization Leading to Arene Chromium Tricarbonyl 1,4-Diradical Intermediates and the Isolation of Indolines

Regiocontrolled synthesis of polysubstituted benzenes from silylated 1,3-dien-5-ynes has been achieved by using diisobutylaluminum hydride (DIBAL-H). Hydroalumination of the...

The thermal cyclization of 3,4-diphenylbuta-1,3-dienyl isocyanates 1, generated in situ from the corresponding azides, was investigated using iodine as a catalyst....

Intramolecular samarium diiodide-induced carbonyl−alkene or carbonyl−alkyne coupling reactions afforded without high dilution conditions 9- and 10-membered benzannulated...

A fascinating mechanistic study of ynamido−palladium−π-allyl complexes is described that features isolation of a unique silyl ketenimine via aza-Claisen rearrangement, which can...

The palladium-catalyzed domino cyclization of propargyl bromides having two nucleophilic functional groups is described. Treatment of 1,7-diamino-5-bromohept-3-yne derivatives...

α-2-Deoxy-d-glucose derived ether 14 is a superior reagent for the allene ether version of the Nazarov cyclization. Enantiomeric excesses of products derived from trisubstituted...

An unusual oxidative cyclization of a N-hydroxy pyridone 9 with Z-2-cyclodecenone 11 has been achieved, thus demonstrating a possible biomimetic route to pyridomacrolidin 2.

Bis Ring Closing Olefin Metathesis for the Synthesis of Unsaturated Polycyclic Ethers. O-Membered Ring Cyclization in Favor of C-Membered Ring Cyclization

Metal-Mediated Cyclization of Aryl and Benzyl Glycidyl Ethers: A Complete Scenario

Moore-Type Cyclization Leading to Arene Chromium Tricarbonyl 1,4-Diradical Intermediates and the Isolation of Indolines

Metal-Mediated Cyclization of Aryl and Benzyl Glycidyl Ethers: A Complete Scenario

Diastereoselective [2 + 2] cyclizations of aldehyde- and ketone-derived silyl enol ethers with acrylates is described. The use of the tris(trimethylsilyl)silyl group allows for...

A simple and effective synthesis of trans aryl-substituted piperazines using a Brønsted acid and manganese(0) is described.

Treatment of diynes with triallylmanganate provided bicyclized products containing a seven-membered ring. N,N-Bis(2-nonynyl)benzylamine gave a mixture of...

A fascinating mechanistic study of ynamido−palladium−π-allyl complexes is described that features isolation of a unique silyl ketenimine via aza-Claisen rearrangement, which can...

W(CO)5·THF-Catalyzed Endo-Selective Cyclization of ω-Acetylenic Silyl Enol Ethers

Intramolecular Friedel−Crafts cyclization of 2-O-benzyl ethers at a model pyranose acetal is activated by incorporation of a trimethylsilyl group, albeit via unexpected,...