9 items found

Groups: Metadata-only Access Tags: Computational Biology

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    Local measles vaccination gaps in Germany and the role of vaccination providers

    Abstract Background Measles elimination in Europe is an urgent public health goal, yet despite the efforts of its member states, vaccination gaps and outbreaks occur. This study...
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    Ancient coexistence of norepinephrine, tyramine, and octopamine signaling in ...

    Abstract Background Norepinephrine/noradrenaline is a neurotransmitter implicated in arousal and other aspects of vertebrate behavior and physiology. In invertebrates,...
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    Nosological delineation of congenital ocular motor apraxia type Cogan: an obs...

    Abstract Background The nosological assignment of congenital ocular motor apraxia type Cogan (COMA) is still controversial. While regarded as a distinct entity by some...
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    Longitudinal estimation of Plasmodium falciparum prevalence in relation to ma...

    Abstract Background Plasmodium falciparum prevalence (PfPR) is a widely used metric for assessing malaria transmission intensity. This study was carried out concurrently with...
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    A systematic review of the clinical presentation, treatment and relapse chara...

    Abstract Background Despite increased efforts to control and ultimately eradicate human malaria, Plasmodium ovale malaria is for the most part outside the focus of research or...
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    Safety and efficacy of the choline analogue SAR97276 for malaria treatment: r...

    Abstract Background Malaria remains one of the most important infectious diseases. Treatment options for severe malaria are limited and the choline analogue SAR97276A is a novel...
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    Vision-related quality of life in patients receiving intravitreal ranibizumab...

    Abstract Background Vision-related quality of life (vrQoL) is advancing more and more into the focus of interest in ophthalmological clinical research. However, to date only...
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    A randomised, double-blind clinical phase II trial of the efficacy, safety, t...

    Abstract Background The clinical development of a single encounter treatment for uncomplicated malaria has the potential to significantly improve the effectiveness of...
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    Microdeletions in 9q33.3-q34.11 in five patients with intellectual disability...

    Abstract Background Most microdeletions involving chromosome sub-bands 9q33.3-9q34.11 to this point have been detected by analyses focused on STXBP1, a gene known to cause early...