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Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer
Background Understanding cell signaling pathways that contribute to metastatic colon cancer is critical to risk stratification in the era of personalized therapeutics. Here, we... -
CTCF maintains regulatory homeostasis of cancer pathways
Background CTCF binding to DNA helps partition the mammalian genome into discrete structural and regulatory domains. Complete removal of CTCF from mammalian cells causes...
