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Suspicion of respiratory tract infection with multidrug-resistant Enterobacte...
Abstract Background Multidrug-resistant (MDR) infections are a serious concern for children admitted to the Paediatric Intensive Care Unit (PICU). Tracheal colonization with MDR... -
Local measles vaccination gaps in Germany and the role of vaccination providers
Abstract Background Measles elimination in Europe is an urgent public health goal, yet despite the efforts of its member states, vaccination gaps and outbreaks occur. This study... -
Infection prevention and control measures and tools for the prevention of ent...
Abstract Background Infections with carbapenem-resistant Enterobacteriaceae (CRE) are increasingly being reported from patients in healthcare settings. They are associated with... -
Longitudinal estimation of Plasmodium falciparum prevalence in relation to ma...
Abstract Background Plasmodium falciparum prevalence (PfPR) is a widely used metric for assessing malaria transmission intensity. This study was carried out concurrently with... -
Demographics of patients receiving Intravitreal anti-VEGF treatment in real-w...
Abstract Background While randomized controlled trials (RCTs) are based on strict inclusion/exclusion criteria, non-interventional studies (NISs) might provide additional... -
Genome-Wide Association Study of Late-Onset Myasthenia Gravis: Confirmation o...
Abstract To investigate the genetics of late-onset myasthenia gravis (LOMG), we conducted a genome-wide association study imputation of >6 million single nucleotide... -
Urinary Neutrophil Gelatinase-Associated Lipocalin (NGAL) and proteinuria pre...
Abstract Background Nephropathia epidemica (NE) is a mild form of hemorrhagic fever with renal syndrome (HFRS) that is caused by the Puumala virus. Periodic outbreaks have been... -
Safety and efficacy of the choline analogue SAR97276 for malaria treatment: r...
Abstract Background Malaria remains one of the most important infectious diseases. Treatment options for severe malaria are limited and the choline analogue SAR97276A is a novel... -
Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pre...
Abstract Background Ipilimumab is an approved immunotherapy that has shown an overall survival benefit in patients with cutaneous metastatic melanoma in two phase III trials. As... -
A randomised, double-blind clinical phase II trial of the efficacy, safety, t...
Abstract Background The clinical development of a single encounter treatment for uncomplicated malaria has the potential to significantly improve the effectiveness of...
