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Updated and standardized genome-scale reconstruction of <i>Mycobacterium tube...
Background The efficacy of antibiotics against M. tuberculosis has been shown to be influenced by experimental media conditions. Investigations of M. tuberculosis growth in... -
Onset, timing, and exposure therapy of stress disorders: mechanistic insight ...
The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system that regulates numerous physiological processes. Disruptions in the activity of the HPA axis are... -
SBMLsqueezer 2: context-sensitive creation of kinetic equations in biochemica...
Background The size and complexity of published biochemical network reconstructions are steadily increasing, expanding the potential scale of derived computational models.... -
Selecting SNPs informative for African, American Indian and European Ancestry...
Background The presence of population structure in a sample may confound the search for important genetic loci associated with disease. Our four samples in the Family... -
A demonstration of modularity, reuse, reproducibility, portability and scalab...
Multi-scale computational modeling is a major branch of computational biology as evidenced by the US federal interagency Multi-Scale Modeling Consortium and major international... -
PATTERNA: transcriptome-wide search for functional RNA elements via structura...
Establishing a link between RNA structure and function remains a great challenge in RNA biology. The emergence of high-throughput structure profiling experiments is...
