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Active Center Control of Termination by RNA Polymerase III and tRNA Gene Tran...
The ability of RNA polymerase (RNAP) III to efficiently recycle from termination to reinitiation is critical for abundant tRNA production during cellular proliferation,... -
<i>tcf7l2</i>, <i>mllt10/af10</i>, and <i>dot1l</i> are essential for Wnt tar...
(A–H) Representative image of BrdU incorporation into epithelial cells in the intestinal bulb of 124 hpf zebrafish embryos. BrdU staining in wild-type embryos (A) and embryos... -
r37980778c78--f0d5c0fd68019e768d8fccd96d8318fb
(A) EU-labelled RNA after UV irradiation shows increase in expression of 47S, as shown by qPCR analysis. (B) RNA of UVC-kinetics used in Fig 1A was further analysed by qPCR.... -
The CSR-1 endogenous RNAi pathway ensures accurate transcriptional reprogramm...
Endogenous RNAi (endoRNAi) is a conserved mechanism for fine-tuning gene expression. In the nematode Caenorhabditis elegans, several endoRNAi pathways are required for the... -
MLLT10/AF10 targets DOT1L-H3K79 methylation to Wnt target genes and is essent...
(A) Expression levels of MLLT10/AF10, β-catenin, DOT1L, and Tubulin analyzed by Western blotting after siRNA depletion of MLLT10/AF10. ChIP experiments in Ls174T CRCs containing... -
dedup_wf_001--28b6f505fdc6caa10deb02d0b360e74e
ToqueFlamenco: a dataset of flamenco guitar falsetas with the corresponding manual transcriptions (.mid) DESCRIPTION This dataset contains a music collection of 15 guitar... -
Specific enrichment of Mllt10/Af10 and Dot1l, and H3K79 methylation at <i>Axi...
(A) Schematic representation of the mouse Axin2 locus and amplicons scanned in Chromatin immunoprecipitation experiments by qPCR. Purified crypt and villus fractions from mouse... -
r37980778c78--070a1745442bb34c98d73b636828e79b
Depletion of mllt10/af10 and dot1l rescues expression of i-fabp in apcmcr/mcr mutant embryos, placing these genes downstream of Apc as Wnt target gene activators (A–N).... -
r37980778c78--ce614e546ede32b94a80857f17dc26dd
Primers used for 5’ flanking sequence cloning, deletion mutant construction, EMSA, mRNA construction and Q-PCR. -
RNase H1 directs origin-specific initiation of DNA replication in human mitoc...
Human mitochondrial DNA (mtDNA) replication is first initiated at the origin of H-strand replication. The initiation depends on RNA primers generated by transcription from an... -
r37980778c78--7f741839c5529792c331284872da70fe
Lysosomes are ubiquitous acidified organelles that degrade intracellular and extracellular material trafficked via multiple pathways. Lysosomes also sense cellular nutrient... -
r37980778c78--fcfa0b7ae1494265c9a887de8330e2eb
The TF binding sites predicted by software online and information for site-directed mutants. -
Frequency of major intermolecular hydrogen bonds during the 50 ns MD trajecto...
MD shows the key role of NTAIL S491 for stable binding to XD. -
r37980778c78--5e6dbe12ea9c8424763a42fd3ded8ce0
(A) Loss of MLLT10/AF10 abrogates TCF/LEF driven transcriptional activation. siRNA mediated depletion of MLLT10/AF10 reduces β-catenin/TCF driven transcription in Ls174T CRCs.... -
Primer sequences used in this study.
IL-6: interleukin-6; ICAM-1: intercellular adhesion molecule-1; TNF-α: tumor necrosis factor-alpha; TGFβ1: transforming growth factor-beta 1; collagen I/III: collagen types... -
Data collection and refinement statistics.
1Statistics for data from the highest-resolution shell are shown in parentheses. 2 R sym =(ΣΣ|Ihkl−〈I〉|)/(ΣIhkl), where the average intensity <I> is taken...
