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Spatiotemporal epidemiology of, and factors associated with, the tuberculosis...
Abstract Background Tuberculosis (TB) is an important public health issue worldwide. However, evidence concerning the impact of environmental factors on TB is sparse. We... -
Improved ascertainment of modes of HIV transmission in Ukraine indicates impo...
Abstract Background It is important to understand how HIV infection is transmitted in the population in order to guide prevention activities and properly allocate limited... -
Patient reported outcomes – experiences with implementation in a University H...
Abstract Aim Patient-reported outcomes (PROs) have traditionally been implemented through a manual process of paper and pencil with little standardization throughout a... -
Bayesian accrual prediction for interim review of clinical studies: open sour...
Abstract Background Subject recruitment for medical research is challenging. Slow patient accrual leads to increased costs and delays in treatment advances. Researchers need... -
Classifying publications from the clinical and translational science award pr...
Abstract Background Translational research is a key area of focus of the National Institutes of Health (NIH), as demonstrated by the substantial investment in the Clinical and... -
Effects of training and support programs for leaders of illness-based support...
Abstract Background Peer-led support groups play an important role in supporting people with chronic diseases. They may be particularly important for people with rare diseases... -
Using predicate and provenance information from a knowledge graph for drug ef...
Abstract Background Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge... -
Statin drugs to reduce breast cancer recurrence and mortality
Abstract Epidemiologic studies have, variably, shown the concomitant use of statin drugs to be beneficial to cancer outcomes. Statin drugs have been FDA approved for three... -
MOdified DIagnostic strateGy to safely ruLe-out pulmonary embolism In the eme...
Abstract Introduction In the work-up strategy for pulmonary embolism (PE) in the ED, the recently introduced YEARS rule allows the raising of the D-dimer threshold to 1000 ng/ml... -
Identifying diabetes cases from administrative data: a population-based valid...
Abstract Background Health care data allow for the study and surveillance of chronic diseases such as diabetes. The objective of this study was to identify and validate optimal... -
Efficacy of a training programme to support the application of the guideline ...
Abstract Background The evidence-based guideline entitled guideline evidence-based health information emerged from the German Network for Evidence-based Medicine (DNEbM) and was... -
Improving enhanced recovery after surgery (ERAS): ERAS APPtimize study protoc...
Abstract Background Perioperative care in colorectal surgery is systematically defined in the Enhanced Recovery After Surgery (ERAS) protocol. The ERAS protocol improves... -
Controlling schistosomiasis with praziquantel: How much longer without a viab...
Abstract The current approach of morbidity control of schistosomiasis, a helminth disease of poverty with considerable public health and socioeconomic impact, is based on... -
Gene name errors are widespread in the scientific literature
Abstract The spreadsheet software Microsoft Excel, when used with default settings, is known to convert gene names to dates and floating-point numbers. A programmatic scan of... -
Buying and selling human eggs: infertility providers’ ethical and other conce...
Abstract Background Egg donor agencies are increasingly being used as part of IVF in the US, but are essentially unregulated, posing critical ethical and policy questions... -
Gene expression prediction using low-rank matrix completion
Abstract Background An exponential growth of high-throughput biological information and data has occurred in the past decade, supported by technologies, such as microarrays and... -
Mapping evidence on malnutrition screening tools for children under 5 years i...
Abstract Background In sub-Saharan Africa (SSA), malnutrition remains a major public health challenge, particularly among children under 5 years of age. Despite nutritional... -
Improving cooperation between general practitioners and dermatologists via te...
Abstract Background Internationally, teledermatology has proven to be a viable alternative to conventional physical referrals. Travel cost and referral times are reduced while... -
Real-time crustal monitoring system of Japanese Islands based on spatio-tempo...
Abstract To continuously monitor crustal behavior associated with earthquakes, magmatic activities and other environmental effects (e.g., tides and rain precipitation), we have... -
Involving general practice trainees in clinical practice guideline adaptation
Abstract Background It is unclear whether it is feasible to involve residents in guideline development or adaptation. We designed a multifaceted training program that combines...