19 items found

Tags: 06 Biological Sciences

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  • publication

    Delivering 21st century Antarctic and Southern Ocean science

    Kennicutt, M.C. et. al.-- 17 pages, 3 figures
  • publication

    Improved tools and strategies for the prevention and control of arboviral dis...

    Background \ud Research has been conducted on interventions to control dengue transmission and respond to outbreaks. A summary of the available evidence will help inform disease...
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    Animal models of chemotherapy-induced peripheral neuropathy: A machine-assist...

    We report a systematic review and meta-analysis of research using animal models of chemotherapy-induced peripheral neuropathy (CIPN). We systematically searched 5 online...
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    How driving endonuclease genes can be used to combat pests and disease vectors

    Driving endonuclease genes (DEGs) spread through a population by a non-Mendelian mechanism. In a heterozygote, the protein encoded by a DEG causes a double-strand break in the...
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    Making transmission models accessible to end-users: The example of TRANSFIL.

    Here, we introduce a newly developed online web interface for the lymphatic filariasis transmission model TRANSFIL, which is validated for Wucheria bancrofti transmission and...
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    Impacts of forests and forestation on hydrological services in the Andes: A s...

    International audience; Several Andean countries have planned to restore forest cover in degraded and deforested land to enhance the provision of multiple ecosystem services in...
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    Bivariate genome-wide association study identifies novel pleiotropic loci for...

    Background: Genome-wide association studies (GWAS) have identified multiple genetic loci for C-reactive protein (CRP) and lipids, of which some overlap. We aimed to identify...
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    A Research Agenda for Helminth Diseases of Humans: Health Research and Capaci...

    Capacity building in health research generally, and helminthiasis research particularly, is pivotal to the implementation of the research and development agenda for the control...
  • publication

    Ten Simple Rules to becoming a principal investigator.

    The biggest choke point in an academic career is going from postdoc to principal investigator (PI): moving from doing someone else’s research to getting other people to do...
  • publication

    "A full-body transcriptome and proteome resource for the European common carp"

    Background The common carp (Cyprinus carpio) is the oldest, most domesticated and one of the most cultured fish species for food consumption. Besides its economic importance,...
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    Distinct core promoter codes drive transcription initiation at key developmen...

    Background Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key component...
  • publication

    MARV: a tool for genome-wide multi-phenotype analysis of rare variants

    Background Genome-wide association studies have enabled identification of thousands of loci for hundreds of traits. Yet, for most human traits a substantial part of the...
  • publication

    The piRNA pathway responds to environmental signals to establish intergenerat...

    Abstract Background piRNAs have a constitutive role in genome defence by silencing transposable elements in the germline. In the nematode Caenorhabditis elegans, piRNAs also...
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    Interpreting ambiguous ‘trace’ results in Schistosoma mansoni CCA Tests: Esti...

    Background The development of new diagnostics is an important tool in the fight against disease. Latent Class Analysis (LCA) is used to estimate the sensitivity and specificity...
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    Reporting Animal Studies: Good Science and a Duty of Care

    In the last decade the number of bioscience journals has increased enormously, with many filling specialised niches reflecting new disciplines and technologies. The emergence of...
  • publication

    Calculating the prevalence of soil-transmitted helminth infection through poo...

    Prevalence is a common epidemiological measure for assessing soil-transmitted helminth burden and forms the basis for much public-health decision-making. Standard diagnostic...
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    Reporting animal research: Explanation and elaboration for the ARRIVE guideli...

    Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve the...
  • publication

    An Eigenvalue test for spatial principal component analysis

    AbstractBackgroundThe spatial Principal Component Analysis (sPCA, Jombart 2008) is designed to investigate non-random spatial distributions of genetic variation. Unfortunately,...
  • publication

    Neuropathic pain and psychological morbidity in patients with treated leprosy...

    Background Neuropathic pain has been little studied in leprosy. We assessed the prevalence and clinical characteristics of neuropathic pain and the validity of the Douleur...