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r37980778c78--b83177d0c6de60e307794c8ade834f8e
l-Fucose, 6-deoxy-l-galactose, is a key component of many important glycoconjugates including the blood group antigens and the LewisX ligands. The biosynthesis of GDP-l-fucose... -
r37980778c78--a53b45f678a186371e2191f6aa1b0375
Due to its function in the rate limiting initial step of the renin-angiotensin system, renin is a particularly promising target for drugs designed to control hypertension, a... -
r37980778c78--088172a2a7cda9b5bc4673bb862e5a4a
From the roots of Lespedeza cyrtobotrya, 45 flavonoids were isolated along with 20 new and 25 known compounds. Lipophilic flavonoids 2, 3, 7, 9, 11, 28, 30, and 39 exhibited... -
Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...
Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a... -
r37980778c78--7119beb953d143ed73039b17787f48f9
This paper reviews in-use emissions from over-the-road heavy-duty (greater than 8500 lb gross vehicle weight) diesel vehicles. Emissions of particulate matter (PM), oxides of... -
r37980778c78--fe9d5df9fcabf325d7c272ad16b6ed9f
Chemical Alternatives Assessment: Enabling Substitution to Safer Chemicals -
A Spray-Processable, Low Bandgap, and Ambipolar Donor−Acceptor Conjugated Pol...
A Spray-Processable, Low Bandgap, and Ambipolar Donor−Acceptor Conjugated Polymer -
Evolving Carbapenemases: Can Medicinal Chemists Advance One Step Ahead of the...
Carbapenems can be an effective treatment of infections with multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa,1 Acinetobacter spp.,2 Klebsiella... -
r37980778c78--1432abdeb57253465dd8e782cca54e4b
A fluorescent deoxyuridine analogue is sensitive to the polarity of its environment and exhibits a distinct emission profile in single- vs double-stranded oligonucleotides.... -
dedup_wf_001--2024910a68cd986b5f7a7319a61f2080
Picrorhizae Rhizoma as a hepatoprotective herb, has been applied for thousands of years, and picroside was proved to be its active constituent. In this study, twelve derivatives... -
Additional file 1: of Imbalanced target prediction with pattern discovery on ...
Supplementary materials of the manuscript. (DOCX 68Â kb) -
Development of a Novel Self-Microemulsifying Drug Delivery System for Reducin...
The development of HIV protease inhibitors (PIs) has been one of the most significant advances of the past decade in controlling HIV infection. Unfortunately, the benefits of... -
dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7
A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary... -
r37980778c78--d5ffa792767440d5d3382b0243ed9f91
The compound trimesic acid (H3TMA) with 2,6-bis(4-pyridylmethylene)cyclohexanone (1) was shown to form two-/three-/four-component cocrystals or salts depending on the reaction... -
r37980778c78--56fcee8741a21a8729fa2db393bd30b0
Design, synthesis, and in vitro bioevaluation of a new class of potential dual PPARα and γ agonists discovered through a structure-driven design paradigm are described. The... -
dedup_wf_001--064ad5f1987610e186aa55df575d4f33
Die eindeutige Zuordnung von Autorinnen und Autoren zu den von ihnen geschaffenen Werken zählt zu den großen Herausforderungen des Publikationsmanagements in der Wissenschaft.... -
r37980778c78--5021c87261f3e825dde9a93ad9814f8e
To develop a novel antipsychotic agent which is an agonist of dopamine (DA) autoreceptors and an antagonist of postsynaptic DA receptors, a series of 7-[4-[4-(substituted... -
r37980778c78--20d5cb9ef2131f7c2f5fd1f5ab7c3f3a
The development of n-pentenyl furanosyl donors has been tested using arabinose as a model. The readily prepared ortho ester (NPOE) is converted into disarmed (NPGAC) and thence... -
r37980778c78--308e0d829603d8f8f45ed47c2eb7a3bc
Exposure to diesel exhaust (DE) has been associated with acute cardiopulmonary and vascular responses, chronic noncancer health effects, and respiratory cancers in humans. To... -
Glycosylation of Smoke-Derived Volatile Phenols in Grapes as a Consequence of...
The presence of glycosides of smoke-derived volatile phenols in smoke-affected grapes and the resulting wines of Chardonnay and Cabernet Sauvignon was investigated with the aid...
