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Associations between skin rash, treatment outcome, and single nucleotide poly...
Purpose: To study the associations between development of moderate to severe skin rash, clinical outcome, and single nucleotide polymorphisms (SNPs) in candidate genes in head... -
A study on the safety and efficacy of reveglucosidase alfa in patients with l...
Background Late-onset Pompe disease is a rare genetic neuromuscular disorder caused by lysosomal acid alpha-glucosidase (GAA) deficiency that ultimately results in mobility loss... -
Blood-flow restricted resistance training in patients with sporadic inclusion...
Objectives: To investigate the effect of 12 weeks of low-load blood-flow restricted resistance (BFR) training on self-reported and objective physical function, and maximal... -
Rising population cost for treating people living with HIV in the UK, 1997-2013.
BACKGROUND\ud \ud The number of people living with HIV (PLHIV) is increasing in the UK. This study estimated the annual population cost of providing HIV services in the UK,... -
Systematic evaluation of the teaching qualities of Obstetrics and Gynecology ...
Background: The importance of effective clinical teaching for the quality of future patient care is globally understood. Due to recent changes in graduate medical education, new... -
A Place to Hide in the Home-Cage Decreases Yolk Androgen Levels and Offspring...
International audience; An animal's emotional responses are the result of its cognitive appraisal of a situation. This appraisal is notably influenced by the possibility of an... -
Broad phenotypic spectrum and genotype-phenotype correlations in GMPPB-relate...
Background Dystroglycanopathy (α-DG) is a relatively common, clinically and genetically heterogeneous category of congenital forms of muscular dystrophy (CMD) and limb-girdle... -
Privacy Attitudes among Early Adopters of Emerging Health Technologies
Introduction Advances in health technology such as genome sequencing and wearable sensors now allow for the collection of highly granular personal health data from individuals.... -
"Expanded HIV Testing in Low-Prevalence, High-Income Countries: A Cost-Effect...
Objective In many high-income countries with low HIV prevalence, significant numbers of persons living with HIV (PLHIV) remain undiagnosed. Identification of PLHIV via HIV... -
Development and differentiability of three brief interventions for risky alco...
Background While brief intervention (BI) for risky alcohol use generally yields positive effects among those identified by screening, effect sizes are small and there is... -
Smoking and response to rituximab in rheumatoid arthritis: results from an in...
Objectives: To investigate whether smoking habits predict response to rituximab (RTX) in rheumatoid arthritis (RA). Method: We included patients from the CERERRA international... -
Updated cost-effectiveness and risk-benefit analysis of two infant rotavirus ...
Background and objective Since 2013, a biennial rotavirus pattern has emerged in the Netherlands with alternating high and low endemic years and a nearly 50% reduction in... -
Feasibility of outpatient total hip and knee arthroplasty in unselected patients
Background and purpose - The number of patients who are suitable for outpatient total hip and knee arthroplasty (THA and TKA) in an unselected patient population remains... -
Publication pressure and burn out among Dutch medical professors: a nationwid...
BACKGROUND: Publication of scientific research papers is important for professionals working in academic medical centres. Quantitative measures of scientific output determine... -
"How much will I get charged for this?" Patient charges for top ten diagnoses...
Objectives We examined the charges, their variability, and respective payer group for diagnosis and treatment of the ten most common outpatient conditions presenting to the... -
Using Normalization Process Theory in feasibility studies and process evaluat...
Background: Normalization Process Theory (NPT) identifies, characterises and explains key mechanisms that promote and inhibit the implementation, embedding and integration of... -
Development and validation of a prognostic model for recurrent glioblastoma p...
Background Predictive markers and prognostic models are required in order to individualize treatment of recurrent glioblastoma (GBM) patients. Here, we sought to identify... -
Health-related quality of life in rectal cancer patients undergoing neoadjuva...
Background: Neoadjuvant chemoradiation with delayed surgery (CRT-DS) and short-course radiotherapy with immediate surgery (SCRT-IS) are two commonly used treatment strategies... -
Trends in alcohol use among young people according to the pattern of consumpt...
Aim To identify differences in Risky Consumption (RC) and Binge drinking (BD) trends in students who already followed these patterns of alcohol consumption on starting... -
Crowd-figure-pictograms improve women’s knowledge about mammography screening...
Objective To evaluate the effect of crowd-figure-pictograms on women’s numeric knowledge about mammography screening in a three-armed parallel randomised controlled trial....
