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A Metal−Organic Framework with a Covalently Prefabricated Porous Organic Linker
We report here the synthesis of a metal−organic framework comprising an organic cage linker with covalently prefabricated, intrinsic porosity. The network can be compared to a... -
The Total Synthesis of Gambierol
This communication describes the total synthesis of the marine polyether toxin, gambierol. This work couples our iterative C-glycoside/enol ether−olefin metathesis strategy to... -
Validation of Protein Structure from Anisotropic Carbonyl Chemical Shifts in ...
Validation of Protein Structure from Anisotropic Carbonyl Chemical Shifts in a Dilute Liquid Crystalline Phase -
Directed Evolution To Investigate Steric Control of Enzymatic Oxidosqualene C...
Directed Evolution To Investigate Steric Control of Enzymatic Oxidosqualene Cyclization. An Isoleucine-to-Valine Mutation in Cycloartenol Synthase Allows Lanosterol and Parkeol... -
MCM-22/Silica Selective Flake Nanocomposite Membranes for Hydrogen Separations
MCM-22/silica composite films were fabricated using layer-by-layer deposition toward a nanoscale realization of the selective flake concept first proposed by Cussler in (J.... -
Donor−Acceptor−Donor-Type Liquid Crystal with a Pyridazine Core
A new liquid crystalline material having an ethylenedioxythiophene−pyridazine−ethylenedioxythiophene (EDOT−PDZ−EDOT) core with two peripheral long alkyl chains was prepared. The... -
Control over Catenation in Metal−Organic Frameworks via Rational Design of th...
Metal−organic frameworks (MOFs), a hybrid class of materials comprising inorganic nodes and organic struts, have potential application in many areas due to their high surface... -
Face-on Oriented Bilayer of Two Discotic Columnar Liquid Crystals for Organic...
2 pages; International audience; In this work, we report the achievement of a homeotropically (or face-on) oriented bilayer formed by a pair of discotic materials designed with... -
Total Synthesis of Tricyclic Azaspirane Derivatives of Tyrosine: FR901483 an...
A solution to the long-standing problem presented by the oxidative cyclization of a phenolic 3-arylpropionamide to a spirolactam has been developed in this laboratory via... -
Type I and Type II Photosensitized Oxidative Modification of 2‘-Deoxyguanosin...
The nucleoside 2‘-deoxyguanosine (dGuo) was treated with 3-(hydroxymethyl)-3,4,4-trimethyl-1,2-dioxetane (HTMD), the latter generates efficiently triplet-excited carbonyl... -
Chiral Bicycle Imidazole Nucleophilic Catalysts: Rational Design, Facile Synt...
A new type of chiral bicycle imidazole nucleophilic catalyst was rationally designed, facilely synthesized, and successfully applied in an asymmetric Steglich rearrangement with... -
Ionic Liquids as Designer Solvents for Nucleophilic Aromatic Substitutions
Ionic liquids were designed to optimize the nucleophilic aromatic substitution reaction of an activated aniline with an activated arylhalide. The design was achieved by... -
Gases as Guests in Benzocyclotrimer Cage Hosts
An imine-linked (+)-syn-benzotricamphor derivative gives access to chiral unimolecular cages exhibiting internal cavities of new shapes and volumes. One of these hosts... -
An easy, inexpensive, and sensitive method for the quantification of chitin i...
Chitin, poly (β-(1→4)-N-acetyl-d-glucosamine), is an important biopolymer for insects that is utilized as a major component of peritrophic membrane. The chitin content in... -
Synthesis of an Analogue of the Marine Polypropionate Tridachiahydropyrone
A novel approach to the formation of the unusual pyrone-containing ring systems as found in polypropionate metabolites from the Tridachia family of marine molluscs has been... -
Enantioconvergent Hydrolysis of Styrene Epoxides by Newly Discovered Epoxide ...
Two novel epoxide hydrolases were discovered in mung bean (Phaseolus radiatus L.) for the first time, either of which can catalyze enantioconvergent hydrolysis of styrene... -
Rational Fine-Tuning of the Redox Potentials in Chemically Synthesized Rubred...
Rational Fine-Tuning of the Redox Potentials in Chemically Synthesized Rubredoxins -
Organocatalytic Asymmetric Vinylogous α-Ketol Rearrangement: Enantioselective...
The catalytic enantioselective synthesis of all-carbon quaternary stereogenic centers in spirocyclic diketones has been achieved for the first time by an unprecedented... -
Cation-Triggered Drug Release from a Porous Zinc−Adeninate Metal−Organic Fram...
A porous anionic metal-organic framework, bio-MOF-1, constructed using adenine as a biomolecular building block is described. The porosity of this material is evaluated, its... -
An Efficient Copper−Aluminum Hydrotalcite Catalyst for Asymmetric Hydrosilyla...
A catalyst system consisting of a copper−aluminum hydrotalcite−chiral diphosphine ligand effects asymmetric hydrosilylation of several ketones, using polymethylhydrosiloxane...
