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Ten-Membered Lactones from the Marine-Derived Fungus <i>Curvularia</i> sp.
Investigation of the secondary metabolites of the marine-derived fungus Curvularia sp. yielded four new 10-membered lactones (1−4), along with the known modiolide A (5). The... -
dedup_wf_001--8a203aab9255a48d912eb8c6ccfd3d36
Further study on the constituents from the stems of Hydrangea paniculata Sieb resulted in isolation of two new compounds 1–2, including 1 monoterpenoid and 1 phenolic glycoside,... -
Tauramamide, a Lipopeptide Antibiotic Produced in Culture byBrevibacillus lat...
Tauramamide (1), a new lipopeptide antibiotic, is produced by cultures of the marine bacterial isolate Brevibacillus laterosporus PNG276 obtained from Papua New Guinea.... -
Two new iridal-type triterpenoids from Iris forrestii
Two new iridal-type triterpenoids, named forrestins A and B (1 and 2), were isolated from Iris forrestii Dykes by comprehensive chromatographic methods. The structures of 1 and... -
New lignans from Urticae Fissae Herba
Two new lignans named neourticol A (1) and neourticol B (2), together with seven known compounds (3–9), were isolated from Urticae Fissae Herba, a folk medicine for rheumatism... -
A cycloartenol synthase from the steroidal saponin biosynthesis pathway of <i...
Steroidal saponins named polyphyllin are the major active components of Paris polyphylla. Cycloartenol synthase (CAS) is a key enzyme that catalyzes the formation of the sterol... -
Hypoxia-Inducible Factor-1 Activation by (−)-Epicatechin Gallate: Potential ...
Hypoxia-inducible factor-1 (HIF-1) is a transcription factor that induces oxygen-regulated genes in response to reduced oxygen conditions (hypoxia). Expression of the... -
Cytotoxic steroid derivatives from the Vietnamese soft coral Sinularia brassica
Using various chromatographic separations, six ergostane-type steroids, including one new compound sinubrassione (1), and two pregnene-type steroid glycosides, including one new... -
β-Carboline Alkaloids from a Korean Tunicate <i>Eudistoma</i> sp.
Seven new β-carboline-based metabolites, designated as eudistomins Y1−Y7 (1−7), were isolated from a tunicate of the genus Eudistoma collected near Tong-Yeong City, South Sea,... -
Notoamide O, a Structurally Unprecedented Prenylated Indole Alkaloid, and Not...
Notoamides O−R were isolated from a marine-derived Aspergillus sp. Notoamide O possesses a novel hemiacetal/hemiaminal ether functionality hitherto unknown among this family of... -
An Endophytic Fungus from <i>Hypericum perforatum</i> that Produces Hypericin
For the first time, an endophytic fungus has been isolated from the stems of the medicinal herb Hypericum perforatum (St. John’s Wort). The fungus produced the napthodianthrone... -
Antiurolithic Effect of Lupeol and Lupeol Linoleate in Experimental Hyperoxal...
The present study was undertaken to explore the efficiency of the pentacyclic triterpene lupeol (1) and its ester derivative, lupeol linoleate (2), in experimental... -
dedup_wf_001--7a1fbadfbdc454ebd5c76bdfd9750acf
A new bile acid tauro-16β-hydroxy-12α-sulfate-5β-cholenoic acid (1), along with six known ones (2–7), was isolated from the snake bile. Its planar structure and relative... -
Constituents from <i><i>Apium graveolens</i></i> and their anti-inflammatory ...
A phthalide glycoside, (3R, 4R)-4-O-β-D-glucopyranosyl-senkyunolide (1), and a megastigmane glycoside, (6S, 7R)-3-oxo-megastigma-4, 8-dien-7-O-β-D-glucoside (2), along with two... -
Ascomycones A−C, Heptaketide Metabolites from an Unidentified Ascomycete
The ascomycones A−C (1−3), three novel heptaketide-derived secondary metabolites, have been isolated from cultures of an unknown ascomycete. While 1 and 2 are closely related...
