β-Carboline Alkaloids from a Korean Tunicate <i>Eudistoma</i> sp.

Seven new β-carboline-based metabolites, designated as eudistomins Y1−Y7 (1−7), were isolated from a tunicate of the genus Eudistoma collected near Tong-Yeong City, South Sea, Korea. These new metabolites differ from previously isolated marine metabolites due to the presence of a benzoyl group attached to the β-carboline nucleus at C-1. Eudistomins Y1−Y7 were evaluated for their antibacterial activity, and eudistomin Y6 exhibited moderate antibacterial activity against Gram-positive bacteria Staphylococcus epidermis and Bacillus subtilis without cytotoxicity in the MTT assay at 100 µM.

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PID https://www.doi.org/10.1021/np070064o
PID https://www.doi.org/10.1021/np070064o.s001
URL https://pubs.acs.org/doi/10.1021/np070064o
URL https://figshare.com/articles/journal_contribution/_Carboline_Alkaloids_from_a_Korean_Tunicate_i_Eudistoma_i_sp_/2955757
URL http://dx.doi.org/10.1021/np070064o
URL https://academic.microsoft.com/#/detail/2037176146
URL https://pubs.acs.org/doi/pdf/10.1021/np070064o
URL https://www.ncbi.nlm.nih.gov/pubmed/18247569
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Access Right Open Access
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Author Wang, Weihong
Author Nam, Sang-Jip
Author Lee, Byoung-Chan
Author Kang, Heonjoong
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Collected From Datacite; figshare; Crossref; Microsoft Academic Graph
Hosted By figshare; Journal of Natural Products
Publication Date 2016-02-27
Publisher American Chemical Society (ACS)
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Language UNKNOWN
Resource Type Other literature type; Article
keyword 100 µ M
system:type publication
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Source https://science-innovation-policy.openaire.eu/search/publication?articleId=dedup_wf_001::ad017bce2c55310ce94f21a8864c3b62
Author jsonws_user
Last Updated 23 December 2020, 07:14 (CET)
Created 23 December 2020, 07:14 (CET)